Lizard tail regeneration as an instructive model of enhanced healing capabilities in an adult amniote

TP Lozito, RS Tuan - Connective tissue research, 2017 - Taylor & Francis
The ability to regenerate damaged or lost tissues has remained the lofty goal of regenerative
medicine. Unfortunately, humans, like most mammals, suffer from very minimal natural …

Appendage regeneration in vertebrates: what makes this possible?

V Daponte, P Tylzanowski, A Forlino - Cells, 2021 - mdpi.com
The ability to regenerate amputated or injured tissues and organs is a fascinating property
shared by several invertebrates and, interestingly, some vertebrates. The mechanism of …

Gekko japonicus genome reveals evolution of adhesive toe pads and tail regeneration

Y Liu, Q Zhou, Y Wang, L Luo, J Yang, L Yang… - Nature …, 2015 - nature.com
Reptiles are the most morphologically and physiologically diverse tetrapods, and have
undergone 300 million years of adaptive evolution. Within the reptilian tetrapods, geckos …

Transcriptome analysis of the regenerating tail vs. the scarring limb in lizard reveals pathways leading to successful vs. unsuccessful organ regeneration in amniotes

N Vitulo, L Dalla Valle, T Skobo, G Valle… - Developmental …, 2017 - Wiley Online Library
Background: Lizards are amniotes regenerating the tail but not the limb, and no information
on their different gene expression is available. Results: Transcriptomes of regenerating tail …

Epi RAD seq: scalable analysis of genomewide patterns of methylation using next‐generation sequencing

DR Schield, MR Walsh, DC Card… - Methods in ecology …, 2016 - Wiley Online Library
Research addressing the role of epigenetics in a diversity of experimental and natural
systems is rapidly accumulating. Diverse methods have been developed to study epigenetic …

[HTML][HTML] Whole transcriptome analysis of the pectoralis major muscle reveals molecular mechanisms involved with white striping in broiler chickens

JAP Marchesi, AMG Ibelli, JO Peixoto, ME Cantão… - Poultry science, 2019 - Elsevier
White striping (WS) is one of the most common myopathies identified in broiler chickens
leading to substantial production losses, where the incidence reaches 12% in commercial …

Animal regeneration in the era of transcriptomics

L Bideau, P Kerner, J Hui, M Vervoort… - Cellular and Molecular …, 2021 - Springer
Animal regeneration, the ability to restore a lost body part, is a process that has fascinated
scientists for centuries. In this review, we first present what regeneration is and how it relates …

Lizard tail skeletal regeneration combines aspects of fracture healing and blastema-based regeneration

TP Lozito, RS Tuan - Development, 2016 - journals.biologists.com
Lizards are amniotes with the remarkable ability to regenerate amputated tails. The early
regenerated lizard tail forms a blastema, and the regenerated skeleton consists of a …

Tail regeneration and other phenomena of wound healing and tissue restoration in lizards

K Jacyniak, RP McDonald… - Journal of Experimental …, 2017 - journals.biologists.com
Wound healing is a fundamental evolutionary adaptation with two possible outcomes: scar
formation or reparative regeneration. Scars participate in re-forming the barrier with the …

Planar cell polarity-mediated induction of neural stem cell expansion during axolotl spinal cord regeneration

A Rodrigo Albors, A Tazaki, F Rost, S Nowoshilow… - elife, 2015 - elifesciences.org
Axolotls are uniquely able to mobilize neural stem cells to regenerate all missing regions of
the spinal cord. How a neural stem cell under homeostasis converts after injury to a highly …