Ceria‐based therapeutic antioxidants for biomedical applications

YG Kim, Y Lee, N Lee, M Soh, D Kim… - Advanced …, 2024 - Wiley Online Library
The growing interest in nanomedicine over the last 20 years has carved out a research field
called “nanocatalytic therapy,” where catalytic reactions mediated by nanomaterials are …

Redox active cerium oxide nanoparticles: current status and burning issues

MS Lord, JF Berret, S Singh, A Vinu, AS Karakoti - Small, 2021 - Wiley Online Library
Research on cerium oxide nanoparticles (nanoceria) has captivated the scientific community
due to their unique physical and chemical properties, such as redox activity and oxygen …

miRNAs as potential game-changers in retinoblastoma: Future clinical and medicinal uses

AS Doghish, HAM Moustafa, MS Elballal… - … -Research and Practice, 2023 - Elsevier
Retinoblastoma (RB) is a rare tumor in children, but it is the most common primitive
intraocular malignancy in childhood age, especially those below three years old. The RB …

[HTML][HTML] A nano-predator of pathological MDMX construct by clearable supramolecular gold (I)-thiol-peptide complexes achieves safe and potent anti-tumor activity

S Yan, J Yan, D Liu, X Li, Q Kang, W You, J Zhang… - Theranostics, 2021 - ncbi.nlm.nih.gov
As alternatives to small-molecular proteolysis-targeting chimeras (PROTAC), peptide-based
molecular glues (MG) are a broad range of dual-functional ligands that simultaneously bind …

GD2-specific CAR T cells encapsulated in an injectable hydrogel control retinoblastoma and preserve vision

K Wang, Y Chen, S Ahn, M Zheng, E Landoni, G Dotti… - Nature cancer, 2020 - nature.com
Retinoblastoma (RB) is a pediatric retinal tumor that overexpresses the ganglioside GD2.
Although it is treatable in patients with early diagnosis, patients may lose one or two eyes …

Ocular nanomedicine

Z Tang, X Fan, Y Chen, P Gu - Advanced Science, 2022 - Wiley Online Library
Intrinsic shortcomings associated with conventional therapeutic strategies often compromise
treatment efficacy in clinical ophthalmology, prompting the rapid development of versatile …

[HTML][HTML] Multi-functionalized nanomaterials and nanoparticles for diagnosis and treatment of retinoblastoma

R Arshad, M Barani, A Rahdar, S Sargazi… - Biosensors, 2021 - mdpi.com
Retinoblastoma is a rare type of cancer, and its treatment, as well as diagnosis, is
challenging, owing to mutations in the tumor-suppressor genes and lack of targeted …

A Ce-MOF@ polydopamine composite nanozyme as an efficient scavenger for reactive oxygen species and iron in thalassemia disease therapy

Y Duan, L Liang, F Ye, S Zhao - Nanoscale, 2023 - pubs.rsc.org
Patients with β-thalassemia are prone to complications such as cardiovascular diseases and
secretory gland injury due to iron overload (IO) and reactive oxygen species (ROS) …

Efficacy of green cerium oxide nanoparticles for potential therapeutic applications: Circumstantial insight on mechanistic aspects

M Khan, ZR Mashwani, M Ikram, NI Raja, AH Mohamed… - Nanomaterials, 2022 - mdpi.com
Green synthesized cerium oxide nanoparticles (GS-CeO2 NPs) have a unique size, shape,
and biofunctional properties and are decorated with potential biocompatible agents to …

Green light‐triggered intraocular drug release for intravenous chemotherapy of retinoblastoma

K Long, Y Yang, W Lv, K Jiang, Y Li, ACY Lo… - Advanced …, 2021 - Wiley Online Library
Retinoblastoma is one of the most severe ocular diseases, of which current chemotherapy is
limited to the repetitive intravitreal injections of chemotherapeutics. Systemic drug …