Current standards of care in glioblastoma therapy

C Fernandes, A Costa, L Osório, RC Lago… - Exon …, 2017 - exonpublications.com
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults.
Regardless of ideal multidisciplinary treatment, including maximal surgical resection …

Current status and recent advances in reirradiation of glioblastoma

G Minniti, M Niyazi, F Alongi, P Navarria, C Belka - Radiation Oncology, 2021 - Springer
Despite aggressive management consisting of maximal safe surgical resection followed by
external beam radiation therapy (60 Gy/30 fractions) with concomitant and adjuvant …

Accelerator-based BNCT for patients with recurrent glioblastoma: a multicenter phase II study

S Kawabata, M Suzuki, K Hirose… - Neuro-oncology …, 2021 - academic.oup.com
Background Boron neutron capture therapy (BNCT) utilizes tumor-selective particle
radiation. This study aimed to assess the safety and efficacy of accelerator-based BNCT (AB …

Mechanisms regulating glioma invasion

I Paw, RC Carpenter, K Watabe, W Debinski, HW Lo - Cancer letters, 2015 - Elsevier
Glioblastoma (GBM) is the most aggressive, deadliest, and most common brain malignancy
in adults. Despite the advances made in surgical techniques, radiotherapy and …

Emerging therapies for glioblastoma

AA Thomas, CW Brennan, LM DeAngelis… - JAMA …, 2014 - jamanetwork.com
Importance Glioblastoma is the most common primary malignant brain tumor, but despite
multimodal treatment with surgery, radiotherapy, and temozolomide chemotherapy, the …

Identification of early response to anti-angiogenic therapy in recurrent glioblastoma: amide proton transfer–weighted and perfusion-weighted MRI compared with …

JE Park, HS Kim, SY Park, SC Jung, JH Kim, HY Heo - Radiology, 2020 - pubs.rsna.org
Background Amide proton transfer (APT) MRI has the potential to demonstrate antitumor
effects by reflecting biologically active tumor portion, providing different information from …

Bevacizumab in recurrent glioma: patterns of treatment failure and implications

Y Li, S Ali, J Clarke, S Cha - Brain tumor research and …, 2017 - synapse.koreamed.org
Glioblastoma, the most common primary malignant brain tumor in adults, is highly
aggressive and associated with a poor prognosis. Bevacizumab, a monoclonal antibody …

Re-irradiation as salvage treatment in recurrent glioblastoma: A comprehensive literature review to provide practical answers to frequently asked questions

S Scoccianti, G Francolini, GA Carta, D Greto… - Critical reviews in …, 2018 - Elsevier
The primary aim of this review is to provide practical recommendations in terms of
fractionation, dose, constraints and selection criteria to be used in the daily clinical routine …

Retrospective analysis of radiological recurrence patterns in glioblastoma, their prognostic value and association to postoperative infarct volume

S Bette, M Barz, T Huber, C Straube, F Schmidt-Graf… - Scientific reports, 2018 - nature.com
Recent studies suggested that postoperative hypoxia might trigger invasive tumor growth,
resulting in diffuse/multifocal recurrence patterns. Aim of this study was to analyze distinct …

Re-irradiation and bevacizumab in recurrent high-grade glioma: an effective treatment option

M Flieger, U Ganswindt, SB Schwarz, FW Kreth… - Journal of neuro …, 2014 - Springer
Re-irradiation has been shown to be a meaningful option for recurrent high-grade glioma
(HGG) patients. Furthermore, bevacizumab exerts certain activity in combination with …