Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives

W Poller, S Dimmeler, S Heymans, T Zeller… - European heart …, 2018 - academic.oup.com
Recent research has demonstrated that the non-coding genome plays a key role in genetic
programming and gene regulation during development as well as in health and …

Extracellular vesicles and their emerging roles as cellular messengers in endocrinology: an endocrine society scientific statement

C Salomon, S Das, U Erdbrügger, R Kalluri… - Endocrine …, 2022 - academic.oup.com
During the last decade, there has been great interest in elucidating the biological role of
extracellular vesicles (EVs), particularly, their hormone-like role in cell-to-cell …

Noncoding RNAs in extracellular fluids as cancer biomarkers: the new frontier of liquid biopsies

B Pardini, AA Sabo, G Birolo, GA Calin - Cancers, 2019 - mdpi.com
The last two decades of cancer research have been devoted in two directions:(1)
understanding the mechanism of carcinogenesis for an effective treatment, and (2) …

The extracellular RNA communication consortium: establishing foundational knowledge and technologies for extracellular RNA research

S Das, AB Abdel-Mageed, C Adamidi, PD Adelson… - Cell, 2019 - cell.com
The Extracellular RNA Communication Consortium (ERCC) was launched to accelerate
progress in the new field of extracellular RNA (exRNA) biology and to establish whether …

Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing

D Buschmann, B Kirchner, S Hermann… - Journal of …, 2018 - Taylor & Francis
Extracellular vesicles (EVs) are intercellular communicators with key functions in
physiological and pathological processes and have recently garnered interest because of …

[HTML][HTML] exceRpt: a comprehensive analytic platform for extracellular RNA profiling

J Rozowsky, RR Kitchen, JJ Park, TR Galeev, J Diao… - Cell systems, 2019 - cell.com
Small RNA sequencing has been widely adopted to study the diversity of extracellular RNAs
(exRNAs) in biofluids; however, the analysis of exRNA samples can be challenging: they are …

A comprehensive profile of circulating RNAs in human serum

SU Umu, H Langseth, C Bucher-Johannessen… - RNA biology, 2018 - Taylor & Francis
Non-coding RNA (ncRNA) molecules have fundamental roles in cells and many are also
stable in body fluids as extracellular RNAs. In this study, we used RNA sequencing (RNA …

The circulating transcriptome as a source of cancer liquid biopsy biomarkers

C Sole, E Arnaiz, L Manterola, D Otaegui… - Seminars in cancer …, 2019 - Elsevier
Non-invasive biomarkers or liquid biopsies have the potential to revolutionise cancer patient
management as repeated sampling allows real-time monitoring of disease progression and …

Chromatin-associated molecular patterns (CAMPs) in sepsis

CP Nofi, P Wang, M Aziz - Cell Death & Disease, 2022 - nature.com
Several molecular patterns have been identified that recognize pattern recognition
receptors. Pathogen-associated molecular patterns (PAMPs) and damage-associated …

The potential of circulating cell-free RNA as a cancer biomarker: challenges and opportunities

IA Zaporozhchenko, AA Ponomaryova… - Expert review of …, 2018 - Taylor & Francis
Introduction: Cancer statistics show that recent improvements in cancer management are
only mildly effective in the absence of reliable biomarkers for the detection, diagnosis and …