Limited antifungal treatment options and drug resistance require innovative approaches to
effectively combat fungal infections. Combination therapy is a promising strategy that …

Aims The unstable antimicrobial activity of antimicrobial peptides (AMPs) under
physiological conditions (especially the degradation instigated proteases) seems to be a …

Pathogenic fungi are an increasing public health concern. The emergence of antifungal
resistance coupled with the scarce antifungal arsenal highlights the need for novel …

Host defense peptide (HDP)-mimicking polymers are promising therapeutic alternatives to
antibiotics and have large-scale untapped potential. Artificial intelligence (AI) exhibits …

The rising prevalence of drug-resistant Gram-positive pathogens, particularly methicillin-
resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) …

Penicillium expansum is the major fungus that causes blue mold and produces patulin,
threatening human health. Due to health and environmental pollution concerns, chitosan …

Intracellular bacterial infections and antimicrobial resistance are threatening global public
health systems. Antimicrobial peptides are a potential solution to combat bacterial …

This study aimed to design a novel antimicrobial peptide, TP I-Y4, through the substitution of
four cysteines with tyrosines in tachyplesin I (TP I), and to investigate its structure-activity …

Antifungal drug resistance is a critical concern, demanding innovative therapeutic solutions.
The dual-targeting mechanism of action (MoA), as an effective strategy to reduce drug …

Poly (2-oxazoline) s (POxs) offer an unparalleled degree of functionalization in the
fabrication of smart, functional polymers for a wide range of applications. By utilizing 2-ethyl …