The 5-year relative survival rate of all types of cancer has increased significantly over the past three decades partly due to the targeted therapy. However, still there are many targeted …
The mere glimpse of venomous animals has always terrified humans because of the devastating effects of their venoms. However, researchers across the globe have isolated …
Cancer represents the disease of the millennium, a major problem in public health. The proliferation of tumor cells, angiogenesis, and the relationship between the cancer cells and …
E dos Santos Nunes, MAA De Souza… - … and Physiology Part B …, 2011 - Elsevier
A novel lectin was isolated from Bothrops leucurus snake venom using a combination of affinity and gel filtration chromatographies. The lectin (BlL) agglutinated glutaraldehyde …
TS Bialves, CLQB Junior, MF Cordeiro… - International Journal of …, 2023 - Elsevier
Despite advances in treating patients with melanoma, there are still many treatment challenges to overcome. Studies with snake venom-derived proteins/peptides describe their …
B Chatterjee - Current topics in medicinal chemistry, 2018 - ingentaconnect.com
The resistance to chemotherapeutics by the cancerous cells has made its treatment more complicated. Animal venoms have emerged as an alternative strategy for anti-cancer …
Snake venoms are a mixture of hydrolases which produce complex pathogenesis such as bleeding, dermo/myonecrosis, inflammation and coagulation disorders. The toxicity of …
C Araya, B Lomonte - Cell biology international, 2007 - Wiley Online Library
The effects of two cationic synthetic peptides, derived from the C‐terminal region of Lys49 phospholipase A2 homologues from snake venoms, upon various murine tumor cell lines …
ES Nunes, MAA Souza, AFM Vaz, TG Silva, JS Aguiar… - Toxicon, 2012 - Elsevier
Neoplastic transformation is the abnormal proliferation of cells. These transformations are often related to changes in cell surface glycoconjugates which can be detected by lectins …