Endocrine disruption by azole fungicides in fish: A review of the evidence

T Huang, Y Zhao, J He, H Cheng… - Science of The Total …, 2022 - Elsevier
Azole fungicides are widely used chemicals in agriculture and medicine. Their antifungal
activity involves inhibition of steroid biosynthesis via inhibition of several cytochrome p 450 …

Priorities and challenges in methodology for human health risk assessment from combined exposure to multiple chemicals

D Nikolopoulou, E Ntzani, K Kyriakopoulou… - Toxics, 2023 - mdpi.com
This paper reviews key elements in the assessment of human health effects from combined
exposure to multiple chemicals taking into consideration current knowledge and challenges …

Health risks of chlorothalonil, carbendazim, prochloraz, their binary and ternary mixtures on embryonic and larval zebrafish based on metabolomics analysis

G Yang, Y Wang, J Li, D Wang, Z Bao, Q Wang… - Journal of Hazardous …, 2021 - Elsevier
Abstract Chlorothalonil (CTL), carbendazim (CBZ), and prochloraz (PCZ) are fungicides
widely used in many countries. The use of these fungicides raises concerns because they …

Dose addition in the induction of craniofacial malformations in zebrafish embryos exposed to a complex mixture of food-relevant chemicals with dissimilar modes of …

LTM Van Der Ven, P Van Ommeren… - Environmental …, 2022 - ehp.niehs.nih.gov
Background: Humans are exposed to combinations of chemicals. In cumulative risk
assessment (CRA), regulatory bodies such as the European Food Safety Authority consider …

Zebrafish models of craniofacial malformations: interactions of environmental factors

ST Raterman, JR Metz, FA Wagener… - Frontiers in Cell and …, 2020 - frontiersin.org
The zebrafish is an appealing model organism for investigating the genetic (G) and
environmental (E) factors, as well as their interactions (GxE), which contribute to craniofacial …

[HTML][HTML] Effect of bisphenol A on craniofacial cartilage development in zebrafish (Danio rerio) embryos: a morphological study

W Huang, X Wang, S Zheng, R Wu, C Liu… - … and Environmental Safety, 2021 - Elsevier
Bisphenol A (BPA), an endocrine-disrupting chemical, is present in everyday-used
consumables and common household products. Although the side effects of BPA have been …

Single and joint toxicity of azoxystrobin and cyproconazole to Prochilodus lineatus: Bioconcentration and biochemical responses

AS Rossi, MP Michlig, MR Repetti… - Science of The Total …, 2024 - Elsevier
Fungicides are widely used across the world to protect crops and their presence in
freshwater systems is increasing. However, the evaluation of their potential impacts on non …

Stereoselective toxicity, bioaccumulation, and metabolic pathways of triazole fungicide cyproconazole in zebrafish

Z He, L Zhou, Y Tan, Z Wang, H Shi, M Wang - Aquatic Toxicology, 2022 - Elsevier
Cyproconazole (CPZ) is a broad-spectrum fungicide that is widely used around the world.
CPZ can persist in water which raised concerns about its potential adverse effects on …

Dieckol, an algae-derived phenolic compound, suppresses airborne particulate matter-induced skin aging by inhibiting the expressions of pro-inflammatory cytokines …

L Wang, WW Lee, TU Jayawardena, SH Cha… - Food and Chemical …, 2020 - Elsevier
Exposure to particulate matter causes skin aging. In the present study, we investigated the
effect of an algae-derived phenolic compound, dieckol (DK), against Chinese particulate …

Cumulative dietary risk assessment of chronic acetylcholinesterase inhibition by residues of pesticides

European Food Safety Authority (EFSA)… - EFSA …, 2021 - Wiley Online Library
A retrospective cumulative risk assessment of dietary exposure to pesticide residues was
conducted for chronic inhibition of acetylcholinesterase. The pesticides considered in this …