Human intervention trials have provided evidence for protective effects of various (poly)
phenol-rich foods against chronic disease, including cardiovascular disease …

Background: There is substantial interest in chocolate and flavan-3-ols for the prevention of
cardiovascular disease (CVD). Objective: The objective was to systematically review the …

Cocoa contains more phenolic antioxidants than most foods. Flavonoids, including catechin,
epicatechin, and procyanidins predominate in antioxidant activity. The tricyclic structure of …

Background: There are very limited data regarding the effects of blueberry flavonoid intake
on vascular function in healthy humans. Objectives: We investigated the impact of blueberry …

Diet is a major life style factor affecting human health, thus emphasizing the need for
evidence-based dietary guidelines for primary disease prevention. While current …

Background: The absorption of cocoa flavanols in the small intestine is limited, and the
majority of the flavanols reach the large intestine where they may be metabolized by …

Flavanol consumption is favorably associated with cognitive function. We tested the
hypothesis that dietary flavanols might improve cognitive function in subjects with mild …

Background High blood pressure is an important risk factor for cardiovascular disease
attributing to about 50% of cardiovascular events worldwide and 37% of cardiovascular …

There is increasing evidence that the consumption of flavonoid-rich foods can beneficially
influence normal cognitive function. In addition, a growing number of flavonoids have been …

Significance: Disruption of endothelial function is considered a key event in the development
and progression of atherosclerosis. Endothelial nitric oxide synthase (eNOS) is a central …