The beneficial roles of SIRT1 in neuroinflammation‐related diseases

F Jiao, Z Gong - Oxidative medicine and cellular longevity, 2020 - Wiley Online Library
Sirtuins are the class III of histone deacetylases whose deacetylate of histones is dependent
on nicotinamide adenine dinucleotide (NAD+). Among seven sirtuins, SIRT1 plays a critical …

Sirt1: role under the condition of ischemia/hypoxia

X Meng, J Tan, M Li, S Song, Y Miao… - Cellular and Molecular …, 2017 - Springer
Silent information regulator factor 2-related enzyme 1 (sirtuin 1, Sirt1) is a nicotinamide
adenine dinucleotide-dependent deacetylase, which can deacetylate histone and non …

Nrf2/antioxidant defense pathway is involved in the neuroprotective effects of Sirt1 against focal cerebral ischemia in rats after hyperbaric oxygen preconditioning

F Xue, J Huang, P Ding, H Zang, Z Kou, T Li… - Behavioural brain …, 2016 - Elsevier
Abstract Sirtuin 1 (Sirt1) is a class III histone deacetylase involved in neuroprotection
induced by hyperbaric oxygen preconditioning (HBO-PC) in animal models of ischemia …

miR-9-5p modulates the progression of Parkinson's disease by targeting SIRT1

Z Wang, L Sun, K Jia, H Wang, X Wang - Neuroscience letters, 2019 - Elsevier
Parkinson's disease (PD) is a most common progressive neurodegenerative disease mainly
occurring in the elderly. Plenty of miRNAs are reported to involve in the progression of PD …

Contra-directional coupling of Nur77 and Nurr1 in neurodegeneration: a novel mechanism for memantine-induced anti-inflammation and anti-mitochondrial …

X Wei, H Gao, J Zou, X Liu, D Chen, J Liao, Y Xu… - Molecular …, 2016 - Springer
Recent evidence suggests that nerve growth factor IB (Nur77) and nuclear receptor related1
(Nurr1) are differentially involved in dopaminergic neurodegeneration. Since memantine …

Sirtuins and their implications in neurodegenerative diseases from a drug discovery perspective

KY Yeong, N Berdigaliyev, Y Chang - ACS chemical neuroscience, 2020 - ACS Publications
Sirtuins are class III histone deacetylase (HDAC) enzymes that target both histone and non-
histone substrates. They are linked to different brain functions and the regulation of different …

An overview of hyperbaric oxygen preconditioning against ischemic stroke

X Wu, J You, X Chen, M Zhou, H Ma, T Zhang… - Metabolic Brain …, 2023 - Springer
Ischemic stroke (IS) has become the second leading cause of morbidity and mortality
worldwide, and the prevention of IS should be given high priority. Recent studies have …

[HTML][HTML] MicroRNA-217/138-5p downregulation inhibits inflammatory response, oxidative stress and the induction of neuronal apoptosis in MPP+-induced SH-SY5Y …

M Wang, H Sun, Y Yao, X Tang… - American Journal of …, 2019 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is a common neurodegenerative disease. Various microRNAs
(miRNAs) have been reported to play important roles in cell growth regulation and …

[PDF][PDF] The Role of Oxidative Stress and Inflammatory Mediators in Benign Paroxysmal Positional Vertigo.

MT Güçlütürk, ZN Ünal, O İsmi… - Journal of …, 2016 - pdfs.semanticscholar.org
OBJECTIVE: Benign paroxysmal positional vertigo (BPPV) is the most common peripheral
cause of vertigo. It can be defined as transient vertigo induced by rapid changes in head …

Adiponectin protects against glutamate‐induced excitotoxicity via activating SIRT1‐dependent PGC‐1α expression in HT22 hippocampal neurons

L Yue, L Zhao, H Liu, X Li, B Wang… - Oxidative medicine …, 2016 - Wiley Online Library
Glutamate‐(Glu‐) induced excitotoxicity plays a critical role in stroke. This study aimed to
investigate the effects of APN on Glu‐induced injury in HT22 neurons. HT22 neurons were …