Osteoarthritis (OA) is a degenerative disease characterized by loss of articular cartilage and
chronic inflammation, involving multiple cellular dysfunctions and tissue lesions. The non …

Osteoarthritis (OA) is the most common degenerative joint disease that causes painful
swelling and permanent damage to the joints in the body. The molecular mechanisms of OA …

The high density structure of cartilage matrix negative charge seriously hinders the
penetration and enrichment of drugs/genes into cartilage tissue. In this study …

Osteoarthritis (OA) is an age-related chronic degenerative joint disease where the main
characteristics include progressive degeneration of cartilage, varying degrees of synovitis …

The Infrapatellar Fat Pad (IFP) is a fibro-adipose tissue of the knee recently reconsidered as
part of a single anatomo-functional unit (AFU) together with the synovial membrane (SM) …

Articular cartilage (AC) has limited capacity for repair. The first attempt to repair cartilage
using tissue engineering was reported in 1977. Since then, cell-based interventions have …

Abstract Purpose of Review Metabolic syndrome (MetS), also called the 'deadly
quartet'comprising obesity, diabetes, dyslipidemia, and hypertension, has been ascertained …

Irregular partial-thickness cartilage defect is a common pathogenesis of osteoarthritis (OA)
with no available treatment in clinical practice. Currently, cartilage tissue engineering is only …

Since inflammatory cytokines cause stress to chondrocytes and the failure of cartilage
defects repair with cartilage tissue engineering, it is necessary to develop a scaffold to …

Objective Synovial fibrosis is a characteristic symptom of osteoarthritis (OA), which is closely
associated with joint pain and stiffness. Previous studies have reported that low-intensity …