Simple Summary The resistance of neoplastic cells to multiple drugs is a serious problem in
cancer chemotherapy. The molecular causes of multidrug resistance in cancer are largely …

Amongst all types of cancers, breast cancer is recognized as the most common cancer and a
principal cause of morbidity and mortality in women. Endoplasmic reticulum (ER) stress …

Nogo-A (Rtn 4A), a member of the reticulon 4 (Rtn4) protein family, is a neurite outgrowth
inhibitor protein that is primarily expressed in the central nervous system (CNS). However …

A large amount of copper (Cu) used in production activities can lead to the enrichment of Cu
in the environment, which can cause toxicity to animals. However, the toxicity mechanism of …

Simple Summary Latrophilin-1 is a latrotoxin receptor and is commonly found in the plasma
membrane of neurons. This receptor has recently been identified in the plasma membrane …

Background: Resistance to standard therapeutic methods, including chemotherapy,
immunotherapy, and targeted therapy, remains a critical challenge in effective cancer …

The expression of the membrane ABCB1 transporter in neoplastic cells is one of the most
common causes of reduced sensitivity to chemotherapy. In our previous study, we …

Ethnopharmacological relevance Lycium barbarum L. and Salvia miltiorrhiza Bunge (Gouqi
and Danshen, LS) have led to their inclusion in the pharmacopoeia and healthcare systems …

In this paper, we compared the effects of bortezomib on L1210 (S) cells with its effects on P-
glycoprotein (P-gp)-positive variant S cells, which expressed P-gp either after selection with …

Four new variants of L1210 cells resistant to endoplasmic reticulum (ER) stressors,
tunicamycin (STun), thapsigargin (SThap), bortezomib (SBor), and MG-132 (SMG-132) …