This review discusses how the T-cell compartment in common variable immunodeficiency is
marked by the premature arrest in thymic output, leading to T-cell exhaustion and immune …

Common variable immunodeficiency (CVID) is a heterogeneous disorder that is associated
with low serum-immunoglobulin concentrations, defective specific-antibody production and …

Background Obesity is a significant risk factor for psoriasis and body mass index (BMI)
correlates with disease severity. Objectives To investigate the relationship between obesity …

Background Autoimmunity has been increasingly recognized as a major issue in patients
with common variable immunodeficiency (CVID), the most common symptomatic primary …

Adiponectin (Acrp30) is an adipokine widely studied for its beneficial metabolic properties. It
circulates as low molecular weight (LMW), medium molecular weight (MMW), and high …

Common variable immunodeficiency is the most prevalent clinically significant antibody
deficiency at all ages. The disorder is defined principally by characteristic infection …

Adiponectin exerts beneficial pleiotropic effects through three receptors, AdipoR1, AdipoR2,
and T-cadherin; it also exerts immunomodulatory effects. We previously demonstrated that …

OBJECTIVES: This study was performed to investigate whether leptin mRNA expression is
increased from peripheral blood mononuclear cells (PBMCs) of patients with active …

Background: Leptin, an adipocyte-derived hormone, has been shown to have several
immunological effects similar to those of proinflammatory cytokines. The relationship …

Both exhaustive physical exertion and starvation have been reported to induce depression
of immune function. The aim of the present study was to investigate the inflammatory …