Oxidative stress has a critical role in the pathophysiology of several kidney diseases, and
many complications of these diseases are mediated by oxidative stress, oxidative stress …

Acute kidney injury (AKI) is a common clinical syndrome that is related to high morbidity and
mortality. Oxidative stress, including the production of reactive oxygen species (ROS) …

Unilateral ureteric obstruction (UUO) is one of the most commonly applied rodent models to
study the pathophysiology of renal fibrosis. This model reflects important aspects of …

Insulin resistance (IR) is present in pathologies such as diabetes, obesity, metabolic
syndrome, impaired glucose tolerance, hypertension, inflammation, cardiac disease, and …

Oxidative stress and inflammation contribute importantly to the pathogenesis of chronic
kidney disease (CKD). Epigallocatechin‐3‐gallate (EGCG), which is the most abundant and …

Background It is well established that renin-angiotensin system (RAS) play a central role in
pathophysiology of renal damage following unilateral ureteral obstruction (UUO). The …

This study aimed to determine the effect of gallic acid (GA) on ameliorating bisphenol A
(BPA) nephrotoxicity in male rat kidneys. Forty rats were assigned randomly into two groups …

Background: Atherosclerosis and its complications represent the leading cause of morbidity
and mortality. Heat shock protein 70 (HSP70) protects cellular elements from injury by …

Perturbation of renal tubular antioxidants and overproduction of reactive oxygen species
may amplify the proinflammatory state of renal obstruction, culminating in oxidative stress …

Glomerulosclerosis frequently complicates most renal diseases and is characterized by
mesangial matrix accumulation. Oxidized low-density lipoprotein (Ox-LDL) could induce …