Atherogenic dyslipidemia after liver transplantation: mechanisms and clinical implications

T Syed, MS Siddiqui - Liver Transplantation, 2021 - Wiley Online Library
Cardiovascular disease (CVD), particularly atherosclerosis‐associated CVD, is a major
cause of long‐term mortality after liver transplantation (LT). The liver is central in lipid …

Saroglitazar improves nonalcoholic fatty liver disease and metabolic health in liver transplant recipients

MS Siddiqui, D Parmar, F Shaikh, M Forsgren… - Liver …, 2023 - journals.lww.com
NAFLD is common after liver transplantation (LT) and is associated with an increased
metabolic burden. Currently, there is a paucity of investigations into the treatment of post-LT …

Differential fuel utilization in liver transplant recipients and its relationship with non‐alcoholic fatty liver disease

MS Siddiqui, S Patel, M Forsgren, AT Bui… - Liver …, 2022 - Wiley Online Library
Metabolic flexibility is the ability to match biofuel availability to utilization. Reduced metabolic
flexibility, or lower fatty acid (FA) oxidation in the fasted state, is associated with obesity. The …

Implications of nonalcoholic steatohepatitis as the cause of end-stage liver disease before and after liver transplant

A Chandrakumaran, MS Siddiqui - Gastroenterology Clinics, 2020 - gastro.theclinics.com
Nonalcoholic fatty liver disease (NAFLD) is the leading cause of increased liver enzyme
levels and has rapidly become the leading cause of chronic liver disease. 1, 2 NAFLD is …

Hepatic steatosis and liver fat contents in liver transplant recipients are associated with serum adipokines and insulin resistance

A Eshraghian, S Nikeghbalian, A Shamsaeefar… - Scientific Reports, 2020 - nature.com
Our data about pathogenesis of hepatic steatosis after liver transplantation is scarce. This
study aimed to investigate the association between serum adipokines and insulin resistance …

Incidence, predictors, and impact on survival of long-term cardiovascular events after liver transplantation

L Sastre, R Garcia, JG Gandara, P Ruiz… - …, 2020 - journals.lww.com
Background: Information on the risk factors, particularly kidney function, and impact of long-
term cardiovascular events (CVE) after liver transplantation (LT) remains scarce. Methods …

Glomerular filtration rate early after liver transplantation independently predicts atherosclerotic events

R Hassouneh, S Patel, S Shen, A Bui… - Liver …, 2022 - Wiley Online Library
Cardiovascular disease (CVD) is an important cause of mortality among liver transplantation
(LT) recipients; however, the data on CVD risk stratification following LT are limited. Thus …

Insulin-independent reversal of type-1 diabetes following transplantation of adult brown adipose tissue supplemented with IGF-1

SC Gunawardana, DW Piston - Transplantation direct, 2019 - journals.lww.com
Background. As our previous publications show, it is feasible to reverse type 1 diabetes
(T1D) without insulin in multiple mouse models, through transplantation of embryonic brown …

Reduced metabolic flexibility is a predictor of weight gain among liver transplant recipients

AT Bui, R Chaudhari, C Bhati, S Wolver… - Liver …, 2024 - journals.lww.com
Metabolic flexibility is the ability to match biofuel availability to utilization and is inversely
associated with increased metabolic burden among liver transplant (LT) recipients. The …

Progression to cirrhosis leads to improvement in atherogenic milieu

S Patel, MB Siddiqui, A Chandrakumaran… - Digestive Diseases and …, 2021 - Springer
Introduction The prevalence of coronary artery disease (CAD) is high among patients with
cirrhosis; however, the impact of it on cardiovascular disease (CVD) is not known. The aim of …