Reactive nitrogen species (RNS), like reactive oxygen species (ROS), are useful for
sustaining reproductive processes such as cell signaling, the regulation of hormonal …

The mast cells are multi-effector cells with wide distribution in the different body parts and
traditionally their role has been well-defined in the development of IgE-mediated …

The testes produce the male gametes and the male sexual hormones (androgens). The term
spermatogenesis describes and includes all the processes involved in the production of …

There is a close functional relationship between the male reproductive and immune
systems. Immunological responses against sperm antigens or other elements of the …

Spermatogenesis is a highly complicated process in which functional spermatozoa (haploid,
1n) are generated from primitive mitotic spermatogonia (diploid, 2n). This process involves …

Gabapentin is an anticonvulsant drug that is also used for post-herpetic neuralgia and
neuropathic pain. Recently, gabapentin showed anti-inflammatory effect. Nuclear factor …

Both subsets of MCs including MCTC (tryptase‐positive, chymase‐positive) and MCT
(tryptase‐positive, chymase‐negative) are present in the testis and epididymis. Increased …

Experimental autoimmune orchitis (EAO) is a chronic inflammatory disorder that causes
progressive spermatogenic impairment. EAO is characterized by high intratesticular levels of …

During an inflammatory process of the testis, the network of somatic, immune, and germ cell
interactions is altered leading to organ dysfunction. In testicular biopsies of infertile men …

This work aimed at identifying mast cells in testicular biopsies from 10 normal fertile controls,
20 patients with obstructive azoospermia and 70 patients with nonobstructive azoospermia …