SARS-CoV-2 triggering autoimmune diseases

L Mobasheri, MH Nasirpour, E Masoumi… - Cytokine, 2022 - Elsevier
Autoimmunity, hyperstimulation of the immune system, can be caused by a variety of
reasons. Viruses are thought to be important environmental elements that contribute to the …

Thrombopoietin receptor agonists (TPO-RAs): drug class considerations for pharmacists

J Gilreath, M Lo, J Bubalo - Drugs, 2021 - Springer
The thrombopoietin receptor agonists (TPO-RAs) romiplostim, eltrombopag, avatrombopag,
and lusutrombopag carry unique US Food and Drug Administration (US FDA)-and European …

A systematic review of reported cases of immune thrombocytopenia after COVID-19 vaccination

P Saluja, FNU Amisha, N Gautam, H Goraya - Vaccines, 2022 - mdpi.com
With the recent outbreak of the COVID-19 pandemic and emergency use authorization of
anti-SARS-CoV-2 vaccines, reports of post-vaccine immune thrombocytopenia (ITP) have …

Assessment and management of immune thrombocytopenia (ITP) in the emergency department: current perspectives

T Zitek, L Weber, D Pinzon, N Warren - Open Access Emergency …, 2022 - Taylor & Francis
Immune thrombocytopenia (ITP) is characterized by a platelet count less than 100× 10^ 9/L
without anemia or leukopenia. Patients with ITP may be asymptomatic, or they may have …

Current understanding of immune thrombocytopenia: a review of pathogenesis and treatment options

A Mititelu, MC Onisâi, A Roșca… - International Journal of …, 2024 - mdpi.com
The management of immune thrombocytopenia (ITP) and the prediction of patient response
to therapy still represent a significant and constant challenge in hematology. ITP is a …

Autoimmune thrombocytopenia: Current treatment options in adults with a focus on novel drugs

M Witkowski, M Witkowska… - European journal of …, 2019 - Wiley Online Library
Immune thrombocytopenia (ITP) is an autoimmune disease characterized by platelet
destruction and reduced platelet production resulting in decreased platelet level and an …

Proteomic‐Based Discovery of Predictive Biomarkers for Drug Therapy Response and Personalized Medicine in Chronic Immune Thrombocytopenia

S Gilanchi, M Faranoush, M Daskareh… - BioMed Research …, 2023 - Wiley Online Library
Purpose. ITP is the most prevalent autoimmune blood disorder. The lack of predictive
biomarkers for therapeutic response is a major challenge for physicians caring of chronic …

[HTML][HTML] Idiopathic thrombocytopenic purpura: current limitations and management

R Thakre, P Gharde, M Raghuwanshi - Cureus, 2023 - ncbi.nlm.nih.gov
Idiopathic thrombocytopenic purpura (ITP), also known as immune thrombocytopenia, is a
blood disorder characterized by a reduction in the number of platelets. A reduction in the …

Dysregulated expression of miRNAs in immune thrombocytopenia

A Jafarzadeh, H Marzban, M Nemati, S Jafarzadeh… - …, 2021 - Taylor & Francis
In recent years the critical role of miRNAs has been established in many diseases, including
autoimmune disorders. Immune thrombocytopenia purpura (ITP) is a predominant …

[HTML][HTML] Romiplostim and eltrombopag in immune thrombocytopenia as a second-line treatment

E Bidika, H Fayyaz, M Salib, AN Memon, AS Gowda… - Cureus, 2020 - ncbi.nlm.nih.gov
Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by platelet count
less than 100× 10 9/L and an increased risk of bleeding. The risk of bleeding increases in …