The estimation of local and structural mechanical properties of bones with micro Finite
Element (microFE) models based on Micro Computed Tomography images depends on the …

Abstract Digital Volume Correlation (DVC) has become popular for measuring the strain
distribution inside bone structures. A number of methodological questions are still open: the …

In vitro mechanical testing of spinal specimens is extremely important to better understand
the biomechanics of the healthy and diseased spine, fracture, and to test/optimize surgical …

Combination of micro-focus computed tomography (micro-CT) in conjunction with in situ
mechanical testing and digital volume correlation (DVC) can be used to access the internal …

The assessment of risk of vertebral fracture in patients with lytic metastases is challenging,
due to the complexity in modelling the mechanical properties of this heterogeneous material …

Pathologies such as cancer metastasis and osteoporosis strongly affect the mechanical
properties of the vertebral bone and increase the risk of fragility fractures. The prediction of …

The strain distribution in vertebral body has been measured in vitro in the elastic regime but
only on the bone surface by means of strain gauges and digital image correlation. Digital …

Background Bone metastases may lead to spine instability and increase the risk of fracture.
Scoring systems are available to assess critical metastases, but they lack specificity, and …

The spine is the first site for incidence of bone metastasis. Thus, the vertebrae have a high
potential risk of being weakened by metastatic tissues. The evaluation of strength of the …

Abstract Currently, the Spinal Instability Neoplastic Score system is used in clinics to
evaluate the risk of fracture in patients with spinal metastases. This method, however, does …