The gut microbiome in depression and potential benefit of prebiotics, probiotics and synbiotics: a systematic review of clinical trials and observational studies

SR Alli, I Gorbovskaya, JCW Liu, NJ Kolla… - International journal of …, 2022 - mdpi.com
An emerging body of literature demonstrates differences in the gut microbiome (GMB) of
patients with major depressive disorder (MDD) compared to healthy controls (HC), as well …

Gut microbiota and major depressive disorder: a systematic review and meta-analysis

K Sanada, S Nakajima, S Kurokawa… - Journal of affective …, 2020 - Elsevier
Background Growing attention has been paid to the field of gut microbiota for mental
disorders over the last decade. However, to our knowledge, no studies have conducted …

Clinical, gut microbial and neural effects of a probiotic add-on therapy in depressed patients: a randomized controlled trial

AC Schaub, E Schneider… - Translational …, 2022 - nature.com
A promising new treatment approach for major depressive disorder (MDD) targets the
microbiota-gut-brain (MGB) axis, which is linked to physiological and behavioral functions …

Gut-brain psychology: rethinking psychology from the microbiota–gut–brain axis

S Liang, X Wu, F Jin - Frontiers in integrative neuroscience, 2018 - frontiersin.org
Mental disorders and neurological diseases are becoming a rapidly increasing medical
burden. Although extensive studies have been conducted, the progress in developing …

Recognizing depression from the microbiota–gut–brain axis

S Liang, X Wu, X Hu, T Wang, F Jin - International journal of molecular …, 2018 - mdpi.com
Major depression is one of the leading causes of disability, morbidity, and mortality
worldwide. The brain–gut axis functions are disturbed, revealed by a dysfunction of the …

Antidepressive mechanisms of probiotics and their therapeutic potential

SJ Yong, T Tong, J Chew, WL Lim - Frontiers in neuroscience, 2020 - frontiersin.org
The accumulating knowledge of the host-microbiota interplay gives rise to the microbiota-gut-
brain (MGB) axis. The MGB axis depicts the interkingdom communication between the gut …

Novel drug developmental strategies for treatment‐resistant depression

É Borbély, M Simon, E Fuchs, O Wiborg… - British journal of …, 2022 - Wiley Online Library
Major depressive disorder is a leading cause of disability worldwide. Because conventional
therapies are ineffective in many patients, novel strategies are needed to overcome …

Protective role of antioxidant supplementation for depression and anxiety: A meta-analysis of randomized clinical trials

H Wang, M Jin, M Xie, Y Yang, F Xue, W Li… - Journal of affective …, 2023 - Elsevier
Background New research supports an integrated approach to treating depression, and
lifestyle modifications should be a regular component of both preventative and treatment …

[HTML][HTML] The efficacy, safety, and tolerability of probiotics on depression: clinical results from an open-label pilot study

CJK Wallace, RV Milev - Frontiers in psychiatry, 2021 - frontiersin.org
Background: A growing body of research has shown that consumption of probiotics can
improve symptoms associated with mood and anxiety disorders through activity of the gut …

Updated review of research on the gut microbiota and their relation to depression in animals and human beings

Z Yang, J Li, X Gui, X Shi, Z Bao, H Han, MD Li - Molecular psychiatry, 2020 - nature.com
The gut microbiota are being called the human “second brain,” as they play a key role in the
regulation of the central nervous system (CNS). Recent findings provide strong evidence for …