The trabecular meshwork (TM) is located in the anterior segment of the eye and is
responsible for regulating the outflow of aqueous humor. Increased resistance to aqueous …

Fuchs endothelial corneal dystrophy (FECD) is the most common primary corneal
endothelial dystrophy and the leading indication for corneal transplantation worldwide …

Primary open angle glaucoma (POAG) is a complex progressive optic nerve neuropathy
triggered by both environmental and genetic risk factors. Several ocular tissues, including …

The main treatment available for restoration of the corneal endothelium is keratoplasty. This
procedure is faced with several difficulties, including the shortage of donor tissue, post …

Central corneal thickness (CCT) is a risk factor of glaucoma, the most common cause of
irreversible blindness worldwide. The identification of genetic determinants affecting CCT in …

Cataracts (opacities of the lens) are frequent in the elderly, but rare in paediatric practice.
Congenital cataracts (in industrialized countries) are mainly caused by mutations affecting …

Keratoconus (KC) is one of the most significant corneal disorders worldwide, characterized
by the progressive thinning and cone-shaped protrusion of the cornea, which can lead to …

Fuchs endothelial corneal dystrophy (FECD) is a leading indication for corneal
transplantation. FECD is characterized by progressive alterations in endothelial cell …

Purpose To study changes in scleral structure induced by chronic experimental intraocular
pressure elevation in mice. Methods We studied the effect of chronic bead-induced …

Recent epidemiological findings and reanalysis of historical data suggest lens opacities
resulting from ionizing radiation exposures are likely induced at lower doses than previously …