Epithelial-mesenchymal transition (EMT) is a crucial, evolutionarily conserved process that
occurs during development and is essential for shaping embryos. Also implicated in cancer …

The WT1 (Wilms' tumour 1) gene encodes a zinc finger transcription factor and RNA-binding
protein that direct the development of several organs and tissues. WT1 manifests both …

An ideal resource for both pediatricians and endocrinologists, Sperling's Pediatric
Endocrinology, 5th Edition, brings you fully up to date with accelerating research; new …

Low levels of the adipocyte-secreted protein adiponectin correlate with albuminuria in both
mice and humans, but whether adiponectin has a causative role in modulating renal disease …

Wilms' tumor, or nephroblastoma, is the most common pediatric renal cancer. The tumors
morphologically resemble embryonic kidneys with a disrupted architecture and are …

Background In women dynamic changes in uterine tissue architecture occur during each
menstrual cycle. Menses, characterised by the shedding of the upper functional layer of the …

Congenital diaphragmatic hernia (CDH) is a severe birth defect and a major cause of
neonatal respiratory distress. Impacting~ 2–3 in 10,000 births, CDH is associated with a high …

During development, the mesoderm maintains a complex relationship with the developing
endoderm giving rise to the mature lung. Pleural mesothelial cells (PMCs) derived from the …

Transcription factor EB (TFEB) represents an emerging player in cancer biology. Together
with microphthalmia‐associated transcription factor, transcription factor E3 and transcription …

Wilms tumors (WT) have provided broad insights into the interface between development
and tumorigenesis. Further understanding is confounded by their genetic, histologic, and …