The conditions under which the Michaelis–Menten equation accurately captures the steady-
state kinetics of a simple enzyme-catalyzed reaction is contrasted with the conditions under …

Sponge-like biomaterials formed from silk fibroin are promising as degradable materials in
clinical applications due to their controllable breakdown into simple amino acids or small …

In biological systems, nonlinear kinetic relationships between metabolites of interest are
modeled for various purposes. Usually, little a priori knowledge is available in such models …

Synthetic Biologists are increasingly interested in the idea of using synthetic feedback
control circuits for the mitigation of perturbations to gene regulatory networks that may arise …

Queueing delays are one very important performance measure for most engineering
network systems. Providing low-delay systems is a major goal of service providers, as it is a …

Models rational in the parameters arise frequently in biosystems and other applications. As
with all models that are non-linear in the parameters, direct parameter estimation, using eg …

Despite linear regression being the most popular statistical modelling technique, in real-life
we often need to deal with situations where the true relationship between the response and …

In this paper, we consider the well known problem of non-linear identification of the rates of
the reactions involved in cells with Monod functions. In bioprocesses, generating data is very …

This paper studies the Michaelis–Menten model (MM), which plays an important role in
pharmacokinetics, from a theoretical as well as a computational point of view. An analytical …

The target of this paper is to review the main Probability models that have been proposed to
examine different problems in (experimental) carcinogenesis. The models have been …