Despite extensive research, pro-angiogenic drugs have failed to translate clinically, and therapeutic angiogenesis, which has potential in the treatment of various cardiovascular …
Stroke is the primary cause of disability due to the brain's limited ability to regenerate damaged tissue. After stroke, an increased inflammatory and immune response coupled …
J Wang, B Li, Z Li, K Ren, L Jin, S Zhang, H Chang… - Biomaterials, 2014 - Elsevier
Inspired by the adhesion strategy of marine mussels, self-polymerization of dopamine under alkaline condition has been proven to be a simple and effective method for surface …
SY Ko, WJ Lee, HA Kenny, LH Dang, LM Ellis… - Communications …, 2019 - nature.com
Cancer-derived small extracellular vesicles (sEVs) induce stromal cells to become permissive for tumor growth. However, it is unclear whether this induction solely occurs …
DW Infanger, ME Lynch… - Annual review of …, 2013 - annualreviews.org
Heterogeneous microenvironmental conditions play critical roles in cancer pathogenesis and therapy resistance and arise from changes in tissue dimensionality, cell-extracellular …
Hematopoietic stem cells (HSCs) are a rare stem cell population found primarily in the bone marrow and responsible for the production of the body's full complement of blood and …
DG Belair, NN Le, WL Murphy - Chemical Communications, 2014 - pubs.rsc.org
Growth factors (GFs) are major regulatory proteins that can govern cell fate, migration, and organization. Numerous aspects of the cell milieu can modulate cell responses to GFs, and …
Biomaterials designed to mimic the intricate native extracellular matrix (ECM) can use a variety of techniques to control the behavior of encapsulated cells. Common methods …
I Guryanov, S Fiorucci, T Tennikova - Materials Science and Engineering …, 2016 - Elsevier
Receptor-ligand interactions (RLIs) are at the base of all biological events occurring in living cells. The understanding of interactions between complementary macromolecules in …