FOXO1 transcription factors affect a number of cell types that are important in the host
response. Cell types whose functions are modulated by FOXO1 include keratinocytes in the …

Insulin plays an indispensable role in the management of hyperglycaemia that arises in a
variety of settings, including Type I and II diabetes, gestational diabetes, as well as is in …

Background and Aims Hepatic macrophages can be activated by many factors such as gut‐
derived bacterial components and factors released from damaged hepatocytes …

Background An uncontrolled inflammatory response is a critical pathophysiological feature
of sepsis. Mesenchymal stem cells (MSCs) induce macrophage phenotype polarization and …

Tumor heterogeneity dominates tumor biological behavior and shapes the tumor
microenvironment. However, the mechanisms of tumor genetic features modulate immunity …

Macrophages polarization plays essential but different roles in most diseases such as
atherosclerosis, adipose tissue inflammation, and insulin resistance. Our previous study …

Gut microbiota and bacterial translocation have been implicated as significant contributors to
mucosal immune responses and tolerance; alteration of microbial molecules, termed …

Hepatic macrophages can be activated by many factors such as gut-derived bacterial
components and factors released from damaged hepatocytes. Macrophage polarization …

Macrophages are plastic cells that can switch among different states according to
bioenergetic or biosynthetic requirements. Our previous work demonstrated that the …

Accumulating evidence has shown that nutrient metabolism is closely associated with the
differentiation and functions of various immune cells. Cellular metabolism, including aerobic …