OBJECTIVE: To estimate the effect of combined heparin and aspirin compared with aspirin
monotherapy in pregnant women with antiphospholipid syndrome and recurrent pregnancy …

Aspirin is one of the most frequently used and cheapest drugs in medicine. It belongs to the
non-steroidal anti-inflammatory drugs with a wide range of pharmacological activities …

BACKGROUND Heparan sulphates play key roles in conception and early pregnancy
events. The role of heparin, a structural analogue, and its application to assisted conception …

BACKGROUND Increased peripheral blood natural killer (NK) cell activity has been
associated with unexplained reproductive failure including recurrent (three or more) …

Stroke is a neurological emergency that carries a risk of morbidity and mortality. Recent
studies have shown that the incidence of stroke, although rare, is increasing in pregnant …

In vitro studies have documented β2 glycoprotein I (β2GPI) binding to endothelial cells (ECs)
and trophoblast using antiphospholipid antibodies. The in vivo binding of β2GPI to these …

The antiphospholipid antibody syndrome (APS) is defined by the persistent presence of
antiphospholipid antibodies in patients with recurrent venous or arterial thromboembolism or …

Background: While medium to high titers of anticardiolipin (aCL) antibodies, defined as> 40
GPL units or> 99th percentile, is a laboratory criteria for the 'definite'diagnosis of …

Objective Pregnancies in women with the antiphospholipid syndrome (APS) are frequently
complicated by fetal loss and intrauterine growth restriction (IUGR). How circulating …

Citation Mulla MJ, Myrtolli K, Brosens JJ, Chamley LW, Kwak‐Kim JY, Paidas MJ, Abrahams
VM. Antiphospholipid antibodies limit trophoblast migration by reducing IL‐6 production and …