Alzheimer's disease (AD) is characterized by cognitive and memory impairments and
neuropathological abnormalities. AD has no cure, inadequate treatment options, and a …

Plaques of amyloid-β (Aβ) and neurofibrillary tangles are the main pathological
characteristics of Alzheimer's disease (AD). However, some older adult people with AD …

Therapeutic options for Alzheimer's disease are limited. Dual compounds targeting two
pathways concurrently may enable enhanced effect. The study focuses on tacrine …

Female sex and Apolipoprotein E (APOE) ε4 genotype are top non-modifiable risk factors for
Alzheimer's disease (AD). Although female-unique experiences like parity (pregnancy and …

Nearly two-thirds of patients with Alzheimer's are women. Identifying therapeutics specific for
women is critical to lowering their elevated risk for developing this major cause of adult …

The 5xFAD mouse model shows age-related weight loss as well as cognitive and motor
deficits. Metabolic dysregulation, especially impaired insulin signaling, is also present in AD …

Background/Objectives: Mental representation of spatial information relies on egocentric
(body-based) and allocentric (environment-based) frames of reference. Research showed …

A series of sulfonyl thioureas 6a–q containing a benzo [d] thiazole ring with an ester
functional group was synthesized from corresponding substituted 2‐aminobenzo [d] …

Background Memory deficits and anxiety symptoms are undesirable effects that occur in
epilepsy patients. They may be associated with the pathophysiology of the disease but also …

To address the problem of neonatal pain-related stress effects on spatial learning, memory
and the stress reactivity of the hypothalamo–pituitary–adrenal axis (the HPA) in adolescent …