Gene therapy has gained significant attention over the past two decades as a potential
method for treating genetic disorders such as severe combined immunodeficiency, 1 cystic …

This review presents an overview of 1→ 2 branched dendrimers and dendrons, created by a
divergent procedure, from their synthesis to modern day applications. The first members of …

We have investigated poly (amidoamine)(PAMAM) dendrimer interactions with supported 1,
2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) lipid bilayers and KB and Rat2 cell …

We report various structural and conformational properties of generations 4, 5, and 6
PAMAM (polyamidoamine) dendrimer [EDA (ethylenediamine) core)] at various protonation …

Isolable, water-soluble gold clusters protected by monolayers of tiopronin (tiopronin− MPCs)
or coenzyme A (CoA− MPCs) were synthesized by a procedure of comparable simplicity to …

Poly (amidoamine)(PAMAM) dendrimers of generations G0, G1, G2, G3, G4, and G6 are
investigated by potentiometric (acid− base) titrations. The data are interpreted with a site …

Objective. To evaluate polypropylenimine dendrimers (generations 1-5: DAB 4, DAB 8, DAB
16, DAB 32, and DAB 64) as gene delivery systems. Methods. DNA binding was evaluated …

Polycationic polymers are used extensively in biology to disrupt cell membranes and thus
enhance the transport of materials into the cell. The highly polydisperse nature of many of …

This work aims to provide an effective and novel solution for the treatment of infection by
using nanovehicles loaded with antibiotics capable of penetrating the bacterial wall, thus …

Extensive simulations of PAMAM dendrimer generation 2 were performed at several pH
conditions with explicit water molecules, to obtain proper conditions and validity for …