The human microbiome in chronic kidney disease: a double-edged sword

E Wehedy, IF Shatat, S Al Khodor - Frontiers in medicine, 2022 - frontiersin.org
Chronic kidney disease (CKD) is an increasing global health burden. Current treatments for
CKD include therapeutics to target factors that contribute to CKD progression, including …

[HTML][HTML] The urinary microbiome and biological therapeutics: Novel therapies for urinary tract infections

C Kenneally, CP Murphy, RD Sleator… - Microbiological …, 2022 - Elsevier
The discovery of microbial communities in the urinary tract (the urobiome) has fundamentally
altered the previous doctrine regarding urine sterility and associated urinary disorders …

Membranous nephropathy: systems biology-based novel mechanism and traditional Chinese medicine therapy

H Miao, Y Zhang, X Yu, L Zou, Y Zhao - Frontiers in pharmacology, 2022 - frontiersin.org
Membranous nephropathy (MN) is a renal-limited non-inflammatory autoimmune disease in
the glomerulus, which is the second or third main cause of end-stage kidney diseases in …

Recurrent urinary tract infections: unraveling the complicated environment of uncomplicated rUTIs

J Josephs-Spaulding, TJ Krogh, HC Rettig… - Frontiers in cellular …, 2021 - frontiersin.org
Urinary tract infections (UTIs) are frequent in humans, affecting the upper and lower urinary
tract. Present diagnosis relies on the positive culture of uropathogenic bacteria from urine …

Culturomics, a potential approach paving the way toward bacteriotherapy

G Matar, M Bilen - Current Opinion in Microbiology, 2022 - Elsevier
The human microbiota has been extensively studied over the past decade to describe its
role in health and diseases. Numerous studies showed the presence of bacterial imbalance …

The urinary tract microbiome in older women exhibits host genetic and environmental influences

AS Adebayo, G Ackermann, RCE Bowyer, PM Wells… - Cell Host & Microbe, 2020 - cell.com
The urinary microbiome is a relatively unexplored niche that varies with gender. Urinary
microbes, especially in aging populations, are associated with morbidity. We present a large …

The bladder is not sterile: an update on the urinary microbiome

AL Ackerman, TC Chai - Current bladder dysfunction reports, 2019 - Springer
Abstract Purpose of Review The article discusses (1) techniques used to study bacterial
urinary microbiota;(2) existence of non-bacterial urinary microbiota;(3) associations between …

Impact of maintenance immunosuppressive therapy on the fecal microbiome of renal transplant recipients: Comparison between an everolimus-and a standard …

G Zaza, A Dalla Gassa, G Felis, S Granata, S Torriani… - PLoS …, 2017 - journals.plos.org
Background The gut microbiome is the full set of microbes living in the gastrointestinal tract
and is emerging as an important dynamic/fluid system that, if altered by environmental …

Urine microbiome in individuals with an impaired immune system

NS Elsayed, AJ Wolfe, RD Burk - Frontiers in Cellular and Infection …, 2024 - frontiersin.org
With the advent of next generation sequencing, it is now appreciated that human urine is not
sterile. Recent investigations of the urinary microbiome (urobiome) have provided insights …

Urobiome: in sickness and in health

B Wojciuk, A Salabura, B Grygorcewicz, K Kędzierska… - Microorganisms, 2019 - mdpi.com
The human microbiome has been proven to contribute to the human condition, both in
health and in disease. The metagenomic approach based on next-generation sequencing …