Hepatocellular carcinoma (HCC) is a major health problem, being the sixth most common
cancer world-wide. Dysregulation of the balance between proliferation and cell death …

Hepatocellular carcinoma (HCC) is the third cause of cancer‐related death worldwide.
Curative options for HCC are limited and exclusively available for patients carrying an early …

Hepatocellular carcinoma (HCC) is a major leading cause of cancer-related death
worldwide. Alpha fetoprotein (AFP) is reactivated in a majority of hepatocellular carcinoma …

The recent discovery of cancer stem cells (CSCs) has played a pivotal role in changing our
view of carcinogenesis and chemotherapy. Based on this concept, CSCs are responsible for …

Deregulated cell proliferation and apoptosis play a major role in hepatocellular carcinoma
(HCC). MicroRNAs participate in the modulation of key molecules linked to …

Hepatic fibrosis is a chronic liver disease that lacks effective pharmacotherapeutic
treatments. As part of the disease's mechanism, hepatic stellate cells (HSCs) are activated …

Liver cirrhosis is the main risk factor for the development of hepatocellular carcinoma (HCC).
Activated hepatic stellate cells (HSC) are the effector cells of hepatic fibrosis and also …

miR-122, a hepato-specific microRNA (miRNA), is frequently down-regulated in human
hepatocellular carcinoma (HCC). In an effort to identify novel miR-122 targets, we performed …

MicroRNAs (miRNAs) constitute a large class of short RNAs (eg, 20–24 nucleotides in
length), whose main function is to posttranscriptionally regulate the expression of protein …

MicroRNAs (miRNA) are small non-coding RNAs that regulate the expression of
approximately 60% of all human genes and play important roles in disease processes …