In the past, metal-based compounds were widely used in the treatment of disease
conditions, but the lack of clear distinction between the therapeutic and toxic doses was a …

Clinical reports have highlighted the radical increase of antibiotic resistance. As a result,
multidrug resistance has emerged as a serious threat to human health. Many organic …

The well-developed synthetic chemistry of ruthenium, particularly with ammine, amine and
imine ligands, provides for many approaches to innovative new metallopharmaceuticals …

Despite the resounding success of cisplatin and closely related platinum antitumor agents, 1-
3 the movement of other transition-metal antitumor agents toward the clinic has been …

Gold nanoparticles may be used in different domains, one of most important being the
biomedical field. They have suitable properties for controlled drug delivery, cancer …

In the next two decades, the world is expected to see around 20 million cases of cancer.
Moreover, the types of cancer will vary considerably from country to other. Therefore, all …

Significant attention has been given to organotin (IV) dithiocabamate compounds in recent
times. This is due to their ability to stabilize specific stereochemistry in their complexes, and …

At present, cisplatin (cis-diamminodichloroplatinum (II)) is one of the most largely employed
anticancer drugs as it is effective in the treatment of 70− 90% of testicular and, in …

This critical review highlights the progress in 195Pt NMR over the last 25 years. In particular,
some of the recent applications of 195Pt NMR in catalytic and mechanistic studies …

Metal ions can bind to DNA directly or indirectly through hydrogen bonding of the
coordinating water molecules surrounding the metal ions. Metal binding to the bases usually …