Nanodiscs in membrane biochemistry and biophysics

IG Denisov, SG Sligar - Chemical reviews, 2017 - ACS Publications
Membrane proteins play a most important part in metabolism, signaling, cell motility,
transport, development, and many other biochemical and biophysical processes which …

Nanodiscs: A toolkit for membrane protein science

SG Sligar, IG Denisov - Protein Science, 2021 - Wiley Online Library
Membrane proteins are involved in numerous vital biological processes, including transport,
signal transduction and the enzymes in a variety of metabolic pathways. Integral membrane …

Applications of high-resolution 1H solid-state NMR

SP Brown - Solid State Nuclear Magnetic Resonance, 2012 - Elsevier
This article reviews the large increase in applications of high-resolution 1H magic-angle
spinning (MAS) solid-state NMR, in particular two-dimensional heteronuclear and …

Recent advances in nanodisc technology for membrane protein studies (2012–2017)

JE Rouck, JE Krapf, J Roy, HC Huff, A Das - FEBS letters, 2017 - Wiley Online Library
Historically, the main barrier to membrane protein investigations has been the tendency of
membrane proteins to aggregate (due to their hydrophobic nature), in aqueous solution as …

Nanodiscs: a controlled bilayer surface for the study of membrane proteins

MA McLean, MC Gregory… - Annual review of …, 2018 - annualreviews.org
The study of membrane proteins and receptors presents many challenges to researchers
wishing to perform biophysical measurements to determine the structure, function, and …

[图书][B] Liposomes, lipid bilayers and model membranes: from basic research to application

G Pabst, N Kucerka, MP Nieh, J Katsaras - 2014 - books.google.com
With contributions from leading researchers in their fields, this book describes state-of-the-
art lipid/model membrane research, and industrial and medical applications, all in one …

[HTML][HTML] Modified lipid and protein dynamics in nanodiscs

K Mörs, C Roos, F Scholz, J Wachtveitl, V Dötsch… - … et Biophysica Acta (BBA …, 2013 - Elsevier
For membrane protein studies, nanodiscs have been shown to hold great potential in terms
of preparing soluble samples while maintaining a lipid environment. Here, we describe the …

Conformational transitions in the membrane scaffold protein of phospholipid bilayer nanodiscs

CR Morgan, CM Hebling, KD Rand, DW Stafford… - Molecular & Cellular …, 2011 - ASBMB
Phospholipid bilayer nanodiscs are model membrane systems that provide an environment
where membrane proteins are highly stable and monodisperse without the use of detergents …

The power, pitfalls and potential of the nanodisc system for NMR-based studies

A Viegas, T Viennet, M Etzkorn - Biological chemistry, 2016 - degruyter.com
The choice of a suitable membrane mimicking environment is of fundamental importance for
the characterization of structure and function of membrane proteins. In this respect, usage of …

Probing the transmembrane structure and topology of microsomal cytochrome-p450 by solid-state NMR on temperature-resistant bicelles

K Yamamoto, M Gildenberg, S Ahuja, SC Im… - Scientific Reports, 2013 - nature.com
Though the importance of high-resolution structure and dynamics of membrane proteins has
been well recognized, optimizing sample conditions to retain the native-like folding and …