Manganese neurotoxicity: new perspectives from behavioral, neuroimaging, and neuropathological studies in humans and non-human primates
TR Guilarte - Frontiers in aging neuroscience, 2013 - frontiersin.org
Manganese (Mn) is an essential metal and has important physiological functions for human
health. However, exposure to excess levels of Mn in occupational settings or from …
health. However, exposure to excess levels of Mn in occupational settings or from …
Neuroimaging in Parkinsonian disorders
M Tripathi, A Kumar, C Bal - Neurology India, 2018 - journals.lww.com
Neuroimaging (NI) in Parkinson's disease (PD) includes functional techniques like positron
emission tomography (PET) and single photon emission computed tomography (SPECT) …
emission tomography (PET) and single photon emission computed tomography (SPECT) …
Non-reference genome transposable elements (TEs) have a significant impact on the progression of the Parkinson's disease
S Kõks, AL Pfaff, LM Singleton… - Experimental …, 2022 - journals.sagepub.com
The pathophysiology of Parkinson's disease (PD) is a complex process of the interaction
between genetic and environmental factors. Studies on the genetic component of PD have …
between genetic and environmental factors. Studies on the genetic component of PD have …
[HTML][HTML] Intrastriatal gradient analyses of 18F-FDOPA PET scans for differentiation of Parkinsonian disorders
GN Stormezand, LT Chaves, DV García, J Doorduin… - NeuroImage: Clinical, 2020 - Elsevier
Abstract Aim L-3, 4-dihydroxy-6–18F-fluorophenylalanine (18F-DOPA PET may be used to
distinguish subjects with Parkinsonism from those with symptoms not originating from …
distinguish subjects with Parkinsonism from those with symptoms not originating from …
Brain 18F-DOPA PET and cognition in de novo Parkinson's disease
Purpose The role of mesocortical dopaminergic pathways in the cognitive function of
patients with early Parkinson's disease (PD) needs to be further clarified. Methods The study …
patients with early Parkinson's disease (PD) needs to be further clarified. Methods The study …
Physiological Whole-Brain Distribution of [18F]FDOPA Uptake Index in Relation to Age and Gender: Results from a Voxel-Based Semi-quantitative Analysis
SR Toch, S Poussier, E Micard, M Bertaux… - Molecular imaging and …, 2019 - Springer
Abstract Purpose 6-[18 F] fluoro-l-DOPA ([18 F] FDOPA), a positron emission tomography
(PET) amino-acid tracer of brain decarboxylase activity, is used to assess the brain …
(PET) amino-acid tracer of brain decarboxylase activity, is used to assess the brain …
Orbitofrontal 18F‐DOPA Uptake and Movement Preparation in Parkinson's Disease
In Parkinson's disease (PD) degeneration of mesocortical dopaminergic projections may
determine cognitive and behavioral symptoms. Choice reaction time task is related to …
determine cognitive and behavioral symptoms. Choice reaction time task is related to …
Dual time point method for the quantification of irreversible tracer kinetics: A reference tissue approach applied to [18F]-FDOPA brain PET
I Lopes Alves, SK Meles… - Journal of Cerebral …, 2017 - journals.sagepub.com
The Patlak graphical analysis (PGAREF) for quantification of irreversible tracer binding with
a reference tissue model was approximated by a dual time point imaging approach …
a reference tissue model was approximated by a dual time point imaging approach …
Biomarker selection and imaging design in cancer: A link with biochemical pathways for imminent engineering
Malignant cells reprogram metabolic pathways to meet the demands of growth and
proliferation. These altered manners of metabolism are now identified as hallmarks of …
proliferation. These altered manners of metabolism are now identified as hallmarks of …
放射性核素显像在帕金森病鉴别诊断中的应用
邓玮玮， 张春银 - 国际放射医学核医学杂志, 2017 - ijrmnm.com
帕金森病(PD) 的鉴别诊断在临床上是一大难题, 放射性核素显像能够为PD 的鉴别诊断提供分子
水平和代谢水平的信息, 有助于PD 与非典型帕金森综合征和特发性震颤(ET) 等疾病的鉴别 …
水平和代谢水平的信息, 有助于PD 与非典型帕金森综合征和特发性震颤(ET) 等疾病的鉴别 …