Coumarin: A natural, privileged and versatile scaffold for bioactive compounds
Many naturally occurring substances, traditionally used in popular medicines around the
world, contain the coumarin moiety. Coumarin represents a privileged scaffold for medicinal …
world, contain the coumarin moiety. Coumarin represents a privileged scaffold for medicinal …
Therapeutic potential of coumarins as antiviral agents
Coumarins have received a considerable attention in the last three decades as a lead
structures for the discovery of orally bioavailable non-peptidic antiviral agents. A lot of …
structures for the discovery of orally bioavailable non-peptidic antiviral agents. A lot of …
Lactones: Classification, synthesis, biological activities, and industrial applications
SK Sartori, MAN Diaz, G Diaz-Muñoz - Tetrahedron, 2021 - Elsevier
This review summarizes the current knowledge on lactones, a class of biologically active
natural products isolated from a wide range of living organisms. Butenolide, 5, 6 …
natural products isolated from a wide range of living organisms. Butenolide, 5, 6 …
A review: Biologically active 3, 4-heterocycle-fused coumarins
The combination of heterocycles offers a new opportunity to create novel multicyclic
compounds having improved biological activity. Coumarins are ubiquitous natural …
compounds having improved biological activity. Coumarins are ubiquitous natural …
Novel fluorescent benzothiazolyl-coumarin hybrids as anti-SARS-COVID-2 agents supported by molecular docking studies: design, synthesis, X-ray crystal structures …
AEM Abdallah, SA Abdel-Latif, GH Elgemeie - ACS omega, 2023 - ACS Publications
This study revealed the design and preparation of new 3-(benzo [d] thiazol-2-yl)-2 H-
chromen-2-one derivatives 9a–h. The structures of the synthesized products were …
chromen-2-one derivatives 9a–h. The structures of the synthesized products were …
Advances in the development of antiviral strategies against parvovirus B19
E Manaresi, G Gallinella - Viruses, 2019 - mdpi.com
Parvovirus B19 (B19V) is a human pathogenic virus, responsible for an ample range of
clinical manifestations. Infections are usually mild, self-limiting, and controlled by the …
clinical manifestations. Infections are usually mild, self-limiting, and controlled by the …
Developing hybrid molecule therapeutics for diverse enzyme inhibitory action: Active role of coumarin-based structural leads in drug discovery
A Ibrar, SA Shehzadi, F Saeed, I Khan - Bioorganic & Medicinal Chemistry, 2018 - Elsevier
Hybrid drugs featuring two or more potentially bioactive pharmacophores have been
recognized as advanced and superior chemical entities to simultaneously modulate multiple …
recognized as advanced and superior chemical entities to simultaneously modulate multiple …
Emerging trends in nanotechnology: Aerogel-based materials for biomedical applications
At present, aerogel is one of the most interesting materials globally. The network of aerogel
consists of pores with nanometer widths, which leads to a variety of functional properties and …
consists of pores with nanometer widths, which leads to a variety of functional properties and …
Coumarins from the peel of citrus grown in Colombia: composition, elicitation and antifungal activity
C Ramírez-Pelayo, J Martínez-Quiñones, J Gil… - Heliyon, 2019 - cell.com
The present work analyses the chromatographic profile of the peels from fruits of different
citrus cultivated in Colombia: sweet orange (Citrus sinensis [L.] Osbeck var. Valencia) …
citrus cultivated in Colombia: sweet orange (Citrus sinensis [L.] Osbeck var. Valencia) …
Novel palladium (II) complexes with iminocoumarin ligands: Synthesis, characterisation, electrochemical behaviour, DFT calculations and biological activities, ADMET …
New Palladium (II) complexes with a series of iminocoumarin derivatives have been
synthesized and characterized by analytical analysis, spectral methods, magnetic …
synthesized and characterized by analytical analysis, spectral methods, magnetic …