Even though diagnosis and management pathways have been substantially improved over
the last years, autoimmune rheumatic diseases (AIRDs) such as rheumatoid arthritis (RA) …

Systemic sclerosis is a connective tissue disease with cutaneous involvement. Clinical
manifestations result from the balance of inflammations/autoimmunity process and …

Objectives PsA is one of the most serious comorbidities associated with psoriasis. While the
early intervention in PsA is demanded, risk factors of PsA development are not well-known …

Objective. To quantify earlier capillary diameter abnormalities, observed by nailfold
videocapillaroscopy (NVC), in primary Raynaud phenomenon (PRP) subjects compared …

Most patients with Raynaud's phenomenon (RP) have “benign” primary RP (PRP), but a
minority have an underlying cause, for example a connective tissue disease such as …

Systemic sclerosis (SSc) is a chronic, systemic disease characterized by fibrosis of the skin
and internal organs, vasculopathy, and auto-immune activation. On the top of severe organ …

Raynaud's phenomenon and digital ulcers (DUs) are frequent among systemic sclerosis
(SSc) patients. Our aim was to investigate the diagnostic and predictive value for DU of …

Background Microvascular involvement plays a decisive role in systemic sclerosis (SSc)
pathogenesis occurring early in the course of the disease. Microangiopathy is responsible of …

Laser speckle contrast analysis (LASCA) is a non-contact technique able to quantify
peripheral blood perfusion (PBP) over large skin areas. LASCA has been used to study …

Tissue turnover, especially in the skin, is altered in systemic sclerosis (SSc), leading to
tissue accumulation. The objective was to examine type III, IV, and VI collagens turnovers in …