T cell acute lymphoblastic leukemia/lymphoma (T-ALL/LBL) is an aggressive malignancy of
progenitor T cells. Despite significant improvements in survival of T-ALL/LBL over the past …

Natural killer (NK) cells play a significant and vital role in the first line of defense against
infection through their ability to target cells without prior sensitization. They also contribute …

Acute lymphoblastic leukemia (ALL) is a malignancy with high heterogeneity in its biological
features and treatments. Although the overall survival (OS) of patients with ALL has recently …

Over the past 20 years natural killer (NK) cell-based immunotherapies have emerged as a
safe and effective treatment option for patients with relapsed or refractory leukemia. Unlike T …

Head and neck squamous cell carcinoma (HNSCC) is a major challenge for current
therapies. CAR-T cells have shown promising results in blood cancers, however, their …

Natural killer (NK) cells make only a small fraction of immune cells in the human body,
however, play a pivotal role in the fight against cancer by the immune system. They are …

Allogeneic natural killer (NK) cell therapies are a valuable treatment option for cancer, given
their remarkable safety and favorable efficacy profile. Although the use of allogeneic donors …

Over many decades, numerous studies have had the common aim of improving cancer
treatments, with several promising approaches proposed. Hepatocellular carcinoma (HCC) …

Ex vivo gene-modified cellular immunotherapy, including chimeric antigen receptor (CAR)-T
and CAR-NK cell therapy, is a promising therapeutic modality for the treatment of various …