Peptides are potential therapeutic alternatives against global diseases, such as
antimicrobial-resistant infections and cancer. Venoms are a rich source of bioactive peptides …

Pain is a common symptom induced during envenomation by spiders and scorpions. Toxins
isolated from their venom have become essential tools for studying the functioning and …

Phα1β (PnTx3–6) is a neurotoxin from the spider Phoneutria nigriventer venom, originally
identified as an antagonist of two ion channels involved in nociception: N-type voltage-gated …

The venom of the “armed” spider Phoneutria nigriventer comprises several potent toxins.
One of the most toxic components from this venom is the neurotoxin PnTx2-6 (LD50=∼ 0.7 …

The word venomics was coined to acknowledge the studies that use omics to investigate
venom proteins and peptides. Venomics has evolved considerably over the last 20 years …

The venoms of arachnids, cone snails, and snakes consist of many peptides that have
various physiological activities, eg, modulation of ion channels. We have recently prepared …

Diabetic neuropathic pain is one of the complications that affect a wide variety of the diabetic
population and is often difficult to treat. Only a small number of patients experience pain …

The venoms of arachnids, cone snails, and snakes consist of many peptides that have
varieties of physiological activities, eg, modulation of ion channels. We have recently …

Many analgesic peptides have been isolated from arthropod species such as spiders and
scorpions and their three-dimensional structures, which are typically stabilized by several …

Background: Phoneutria nigriventer venom contains Phα1β. This toxin and its recombinant
form have a remarkable analgesic potential that is associated with blockage of voltage …