Recent advances in the biosensing of neurotransmitters: material and method overviews towards the biomedical analysis of psychiatric disorders

A Mobed, M Hasanzadeh, A Ahmadalipour… - Analytical …, 2020 - pubs.rsc.org
Neurotransmitters are the most important messengers of the nervous system, and any
changes in their balances and activities can cause serious neurological, psychiatric and …

Bi-enzymatic biosensor for on-site, fast and reliable electrochemical detection of relevant D-amino acids in bacterial samples

M Moreno-Guzman, L García-Carmona… - Sensors and Actuators B …, 2017 - Elsevier
In this work, a bi-enzymatic biosensor allowed the total content of D-amino acids (DAAs)
determination in highly relevant matrices involving bacteria. The strategy is based on the …

Estimation of the antioxidative properties of amino acids-an electrochemical approach

A Masek, E Chrzescijanska, M Zaborski - International Journal of …, 2014 - Elsevier
The study antioxidant properties of amino acids is very important, because they are the
building blocks of peptides and proteins, and they take part in many fundamental …

[HTML][HTML] Characterisation of a microelectrochemical biosensor for real-time detection of brain extracellular d-serine

MM Doran, KP Bermingham, MD Tricklebank, JP Lowry - Talanta, 2024 - Elsevier
A modified development protocol and concomitant characterisation of a first generation
biosensor for the detection of brain extracellular d-serine is reported. Functional parameters …

Localized Detection of d‐Serine by using an Enzymatic Amperometric Biosensor and Scanning Electrochemical Microscopy

D Polcari, SC Perry, L Pollegioni, M Geissler… - …, 2017 - Wiley Online Library
Abstract d‐Serine acts as an endogenous co‐agonist for N‐methyl‐d‐aspartate receptors at
synapses, making it essential for proper brain development and function. This amino acid …

Editors' Choice—A Miniaturized Enzymatic Biosensor for Detection of Sensory-Evoked D-serine Release in the Brain

S Moussa, MR Van Horn, A Shah… - Journal of The …, 2021 - iopscience.iop.org
D-serine has been implicated as a brain messenger with central roles in neural signaling
and plasticity. Disrupted levels of D-serine in the brain have been associated with …

A Rationally and Computationally Designed Fluorescent Biosensor for d-Serine

V Vongsouthi, JH Whitfield, P Unichenko… - ACS …, 2021 - ACS Publications
Solute-binding proteins (SBPs) have evolved to balance the demands of ligand affinity,
thermostability, and conformational change to accomplish diverse functions in small …

Quantitative measurements of free and immobilized RgDAAO Michaelis-Menten constant using an electrochemical assay reveal the impact of covalent cross-linking …

S Moussa, D Chhin, L Pollegioni… - Analytical and Bioanalytical …, 2021 - Springer
Challenges facing enzyme-based electrochemical sensors include substrate specificity,
batch to batch reproducibility, and lack of quantitative metrics related to the effect of enzyme …

Selective Oxidation of d-Amino Acids Catalyzed by Oligolamellar Liposomes Intercalated with d-Amino Acid Oxidase

M Yoshimoto, M Okamoto, K Ujihashi, T Okita - Langmuir, 2014 - ACS Publications
d-Amino acid oxidase (DAO) is structurally unstable and exhibits broad specificity to d-amino
acids. In this work, we fabricated a stable liposomal DAO system with high apparent …

d-Serine Uptake and Release in PC-12 Cells Measured by Chiral Microchip Electrophoresis-Mass Spectrometry

X Li, C McCullum, S Zhao, H Hu… - ACS chemical …, 2015 - ACS Publications
Previous work has established that d-serine (d-Ser) plays important roles in certain
neurological processes. Study on its uptake/storage and release by neuronal cells is highly …