MRD in ALL: Optimization and Innovations

E Pierce, B Mautner, J Mort, A Blewett, A Morris… - Current Hematologic …, 2022 - Springer
Abstract Purpose of Review Measurable residual disease (MRD) is an important monitoring
parameter that can help predict survival outcomes in acute lymphoblastic leukemia (ALL) …

[HTML][HTML] Evaluation of MicroRNA as Minimal Residual Disease in Leukemia: Diagnostic and Prognostic Approach: A Review

BS Amiri, N Sabernia, B Abouali, P Amini… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Various factors are effective in the development of minimal residual disease (MRD), one of
which is MicroRNAs (miRNAs). miRNAs and their dysfunction in gene expression have …

Clinical impact of measurable residual disease in Acute myeloid leukemia

T Azenkot, BA Jonas - Cancers, 2022 - mdpi.com
Simple Summary Advances in immunophenotyping and molecular techniques have allowed
for the development of more sensitive diagnostic tests in acute leukemia. These techniques …

Droplet digital PCR for sensitive relapse detection in acute myeloid leukaemia patients transplanted by reduced intensity conditioning

JK Gronlund, C Veigaard… - European Journal of …, 2024 - Wiley Online Library
Introduction Follow‐up after allogeneic transplantation in acute myeloid leukaemia (AML) is
guided by measurable residual disease (MRD) testing. Quantitative polymerase chain …

Acute myeloid leukemia stem cells in minimal/measurable residual disease detection

K Srinivasan Rajsri, N Roy, S Chakraborty - Cancers, 2023 - mdpi.com
Simple Summary Leukemia stem cells (LSCs) are rare cell populations present in acute
myeloid leukemia (AML) that are resistant to chemotherapy and cause disease relapse in …

Measurable residual disease monitoring by ddPCR in the early posttransplant period complements the traditional MFC method to predict relapse after HSCT in AML …

W Chen, J Huang, Y Zhao, L Huang, Z Yuan… - Journal of Translational …, 2024 - Springer
Abstract Background Droplet digital PCR (ddPCR) is widely applied to monitor measurable
residual disease (MRD). However, there are limited studies on the feasibility of ddPCR-MRD …

Prediksi Kanker Darah Menggunakan Metode Convolutional Neural Network

H Istiqomah, P Purwono, R Ardianto - Jurnal Ilmu Komputer dan …, 2024 - jiki.jurnal-id.com
Leukemia pada anak-anak di Indonesia menjadi perhatian serius dalam bidang kesehatan
karena variasi tingkat kelangsungan hidup dan dampak negatif dari pengobatan. Penelitian …

Optimizing maintenance therapy in acute myeloid leukemia: where do we stand in the year 2024?

C Alati, M Pitea, MC Mico, V Marafioti… - Expert Review of …, 2024 - Taylor & Francis
Introduction Despite the prognosis of patients affected by acute myeloid leukemia (AML)
improved in the last decade, most patients relapse. Maintenance therapy after a …

Consensus-Based Guidelines for Acute Myeloid Leukemia Management in Gulf Cooperation Council Countries: Addressing Unmet Regional Needs and the …

MK Al-Khabori, A Alhuraiji, AR Alam, FA Khan… - JCO Global …, 2024 - ascopubs.org
PURPOSE AML is a heterogeneous hematologic malignancy. Region-specific
recommendations for AML management can enhance patient outcomes. This article aimed …

Ultrasensitive quantitation of FLT3-ITD mutation in patients with acute myeloid leukemia using ddPCR

AA Kojabad, R Chegeni, S Rostami, F Zaker… - Molecular Biology …, 2023 - Springer
Background FLT3-ITD mutations occur in 45–50% of cytogenetically normal AML patients.
Conventional fragment analysis using capillary electrophoresis is routinely used to …