Lymphatic vessels are low-pressure, blind-ended tubular structures that play a crucial role in
the maintenance of tissue fluid homeostasis, immune cell trafficking, and dietary lipid uptake …

In recent years, the study of lymphangiogenesis and fibrotic diseases has made
considerable achievements, and accumulating evidence indicates that lymphangiogenesis …

Kidneys are highly vascular organs that despite their relatively small size receive 20% of the
cardiac output. The highly intricate, delicately organized structure of renal microcirculation is …

The lymphatic system (or lymphatics) consists of lymphoid organs and lymphatic vessels.
Despite the numerous previously published studies describing conditions related to …

Tertiary lymphoid tissues (TLTs) are inducible ectopic lymphoid tissues that develop at sites
of chronic inflammation in nonlymphoid organs. As with lymph nodes, TLTs initiate adaptive …

The lymphatic system is an integral part of the circulatory system and plays an important role
in the fluid homeostasis of the human body. Accumulating evidence has recently suggested …

Background Lymphatic abnormalities are observed in several types of kidney disease, but
the relationship between the renal lymphatic system and renal function is unclear. The …

Expansion of renal lymphatic networks, or lymphangiogenesis (LA), is well recognized
during development and is now being implicated in kidney diseases. Although LA is …

Similar to other organs, renal lymphatics remove excess fluid, solutes, and macromolecules
from the renal interstitium. Given the kidney's unique role in maintaining body fluid …

Background: The inflammatory response to acute kidney injury (AKI) likely dictates future
renal health. Lymphatic vessels are responsible for maintaining tissue homeostasis through …