CSF1R and BTK inhibitions as novel strategies to disrupt the dialog between mantle cell lymphoma and macrophages

A Papin, B Tessoulin, C Bellanger, A Moreau, Y Le Bris… - Leukemia, 2019 - nature.com
The microenvironment strongly influences mantle cell lymphoma (MCL) survival,
proliferation, and chemoresistance. However, little is known regarding the molecular …

[HTML][HTML] The IL32/BAFF axis supports prosurvival dialogs in the lymphoma ecosystem and is disrupted by NIK inhibition

S Decombis, A Papin, C Bellanger, C Sortais… - …, 2022 - ncbi.nlm.nih.gov
Aggressive B-cell malignancies, such as mantle cell lymphoma (MCL), are
microenvironment-dependent tumors and a better understanding of the dialogs occurring in …

Crosstalk between ROR1 and BCR pathways defines novel treatment strategies in mantle cell lymphoma

H Karvonen, D Chiron, W Niininen, S Ek… - Blood …, 2017 - ashpublications.org
Mantle cell lymphoma (MCL) is an aggressive form of non-Hodgkin B-cell lymphoma with
poor prognosis due to drug resistance. Introduction of the Bruton tyrosine kinase (BTK) …

Racial and socioeconomic disparities in mantle cell lymphoma

NN Shah, Y Xi, Y Liu, JL Koff, CR Flowers… - … Myeloma and Leukemia, 2019 - Elsevier
Background Although race and socioeconomic factors are associated with outcome in many
malignancies, few studies have examined the effect of race and socioeconomic status on …

The MYRACLE protocol study: a multicentric observational prospective cohort study of patients with multiple myeloma

L Benaniba, B Tessoulin, S Trudel… - BMC cancer, 2019 - Springer
Background Despite recent advances in the treatment of multiple myeloma, the disease
constantly relapses and is still considered as incurable. The current knowledge about the …

Whole genome copy number analysis in search of new prognostic biomarkers in first line treatment of mantle cell lymphoma. A study by the LYSA group

Y Le Bris, F Magrangeas, A Moreau… - Hematological …, 2020 - Wiley Online Library
Mantle cell lymphoma (MCL) is a lymphoproliferative disorder characterized by the t (11;
14)(q13; q32) CCND1/IGH translocation. This lymphoma is however extremely …

Pre‐treatment health‐related quality of life parameters have prognostic impact in patients> 65 years with newly diagnosed mantle cell lymphoma: The Nordic …

Å Lindberg, CW Eskelund… - Hematological …, 2022 - Wiley Online Library
Mantle cell lymphoma (MCL) is a rare, often aggressive type of B‐cell lymphoma with poor
survival and no cure. Cancer and cancer treatment has a negative impact on health‐related …

[PDF][PDF] Habilitation à Diriger les Recherches _ Habilitation à Diriger les Recherches

D Chiron - 2022 - inserm.hal.science
Mantle cell lymphoma (MCL), a non-Hodgkin lymphoma of pregerminal center mature B
cells, remains incurable due to the development of drug resistance (1). Bruton tyrosine …

[PDF][PDF] Whole genome copy number analysis in search of new prognostic biomarkers in first line treatment of mantle cell lymphoma. A study by the LYSA group.

OH Deceunynck, MH Delfau-Larue13, B Tessoulin… - researchgate.net
Mantle cell lymphoma (MCL) is a lymphoproliferative disorder characterized by the t (11;
14)(q13; q32) CCND1/IGH translocation. This lymphoma is however extremely …

[HTML][HTML] CSF1R and BTK inhibitions as novel strategies to disrupt the dialogue between mantle cell lymphoma and macrophages

A Papin, B Tessoulin, C Bellanger, A Moreau, YLE Bris… - Blood, 2018 - Elsevier
The aggressive clinical behavior of mantle cell lymphoma (MCL) and its short-term response
to treatments highlight a need for novel options. The microenvironment strongly controls …