Mesenchymal stem cells engineered for cancer therapy

K Shah - Advanced drug delivery reviews, 2012 - Elsevier
Recent pre-clinical and clinical studies have shown that stem cell-based therapies hold
tremendous promise for the treatment of human disease. Mesenchymal stem cells (MSC) …

Differential effects of extracellular vesicles secreted by mesenchymal stem cells from different sources on glioblastoma cells

A Del Fattore, R Luciano, R Saracino… - Expert opinion on …, 2015 - Taylor & Francis
Background: Malignant glial tumors, including glioblastoma multiforme, account for 15–20%
of pediatric CNS malignancies. They are most resistant to therapy and are associated with a …

Mesenchymal stem cells as therapeutics and vehicles for gene and drug delivery

CD Porada, G Almeida-Porada - Advanced drug delivery reviews, 2010 - Elsevier
Mesenchymal stem cells (MSCs) possess a set of several fairly unique properties which
make them ideally suited both for cellular therapies/regenerative medicine, and as vehicles …

The future of mesenchymal stem cell-based therapeutic approaches for cancer–from cells to ghosts

A Mohr, R Zwacka - Cancer letters, 2018 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent stromal cells which can differentiate into a
variety of cell types including osteoblasts, adipocytes and chondrocytes. They are normally …

Therapeutic mesenchymal stromal cells for immunotherapy and for gene and drug delivery

G Almeida-Porada, AJ Atala, CD Porada - Molecular Therapy-Methods & …, 2020 - cell.com
Mesenchymal stromal cells (MSCs) possess several fairly unique properties that, when
combined, make them ideally suited for cellular-based immunotherapy and as vehicles for …

Intra-arterial delivery of cell therapies for stroke

R Guzman, M Janowski, P Walczak - Stroke, 2018 - Am Heart Assoc
2 Stroke May 2018 so the trophic function of capillaries is maintained. Although some
degree of temporary capillary blockage may be tolerated, if a critical threshold is exceeded …

Magnetically-assisted viral transduction (magnetofection) medical applications: An update

B Azadpour, N Aharipour, A Paryab, H Omid… - Biomaterials …, 2023 - Elsevier
Gene therapy involves replacing a faulty gene or adding a new gene inside the body's cells
to cure disease or improve the body's ability to fight disease. Its popularity is evident from …

Impact of Indium-111 Oxine Labelling on Viability of Human Mesenchymal Stem Cells In Vitro, and 3D Cell-Tracking Using SPECT/CT In Vivo

FJ Gildehaus, F Haasters, I Drosse, E Wagner… - Molecular Imaging and …, 2011 - Springer
Purpose This study investigates the effects of 111 In-oxine incorporation on human
mesenchymal stem cells'(hMSC) biology and viability, and the applicability of 111 In-oxine …

[HTML][HTML] Multimodality reporter gene imaging: Construction strategies and application

M Li, Y Wang, M Liu, X Lan - Theranostics, 2018 - ncbi.nlm.nih.gov
Molecular imaging has played an important role in the noninvasive exploration of multiple
biological processes. Reporter gene imaging is a key part of molecular imaging. By …

Imaging long-term fate of intramyocardially implanted mesenchymal stem cells in a porcine myocardial infarction model

EC Perin, M Tian, FC Marini III, GV Silva, Y Zheng… - PLoS …, 2011 - journals.plos.org
The long-term fate of stem cells after intramyocardial delivery is unknown. We used
noninvasive, repetitive PET/CT imaging with [18F] FEAU to monitor the long-term (up to 5 …