Schizophrenia (SCZ) is a complex psychiatric disorder with severe impact on patient's
livelihood. In the last years, the importance of neuropeptides in SCZ and other CNS …

Background To date, besides genome-wide association studies, a variety of other genetic
analyses (eg polygenic risk scores, whole-exome sequencing and whole-genome …

So far, over 20 causative genes of monogenic Parkinson's disease (PD) have been
identified. Some causative genes of non-parkinsonian entities may also manifest with …

Lithium is an effective, well-established treatment for bipolar disorder (BD). However, the
mechanisms of its action, and reasons for variations in clinical response, are unclear. We …

The vast use of corticosteroids (CCSs) globally has led to an increase in CCS-induced
neuropsychiatric disorders (NPDs), a very common manifestation in patients after CCS …

Metabotropic glutamate receptor 1 (mGluR1) plays a crucial role in slow excitatory
postsynaptic conductance, synapse formation, synaptic plasticity, and motor control. The …

Rare mutations associated with schizophrenia (SZ) and bipolar disorder (BD) usually have
high clinical penetrance; however, they are highly heterogeneous and personalized …

Recent data described that patients with lysosomal storage disorders (LSDs) may have
clinical schizophrenia (SCZ) features. Disruption of lipid metabolism in SCZ pathogenesis …

We investigated the genetic causes of major mental disorders (MMDs) including
schizophrenia, bipolar disorder I, major depressive disorder and attention deficit hyperactive …

Аннотация Поиск новых подходов к классификации психических заболеваний—одна из
приоритетных задач современной психиатрии. Предложенные на сегодняшний день …