Innate immunity is the first line of the host immune system to fight against infections. Natural
killer cells are the innate immunity lymphocytes responsible for fighting against virus …

Ebola virus (EBOV) disease can result in a range of symptoms anywhere from virtually
asymptomatic to severe hemorrhagic fever during acute infection. Additionally, spans of …

The ex vivo activation and proliferation of cytotoxic T cells are critical steps in adoptive
immunotherapy. Today, T cells are activated by stimulation with antibody-coated magnetic …

Accumulation of activated natural killer (NK) cells in tissues during Ebola virus infection
contributes to Ebola virus disease (EVD) pathogenesis. Yet, immunization with Ebola virus …

Nuclear factor–ĸB (NF-ĸB) transcription factor is a family of essential regulators of the
immune response and cell proliferation and transformation. A typical factor is a heterodimer …

The use of passively-administered neutralizing antibodies is a promising approach for the
prevention and treatment of SARS-CoV-2 infection. Antibody-mediated protection may …

The innate lymphocyte lineage natural killer (NK) is now the target of multiple clinical
applications, although none has received an agreement from any regulatory agency yet …

The Ebola Virus (EBOV) glycoprotein (GP) sterically shields cell-membrane ligands to
immune receptors such as human leukocyte antigen class-1 (HLA-I) and MHC class I …

Highlights•Emerging viruses avoid immune recognition by dampening early pro-
inflammatory responses.•Natural hosts of zoonotic viruses have developed enhanced …

Ebola virus disease targets and destroys immune cells, including macrophages and
dendritic cells, leading to impairment of host response. After infection, a combination of …