Venomics of Naja sputatrix, the Javan spitting cobra: A short neurotoxin-driven venom needing improved antivenom neutralization

NH Tan, KY Wong, CH Tan - Journal of proteomics, 2017 - Elsevier
The venom proteome of Naja sputatrix (Javan spitting cobra) was elucidated through
reverse-phase HPLC, nano-ESI-LCMS/MS and data mining. A total of 97 distinct protein …

Elucidating the biogeographical variation of the venom of Naja naja (spectacled cobra) from Pakistan through a venom-decomplexing proteomic study

KY Wong, CH Tan, KY Tan, NH Quraishi, NH Tan - Journal of proteomics, 2018 - Elsevier
Naja naja is a medically important species that is distributed widely in South Asia. Its venom
lethality and neutralization profile have been reported to vary markedly, but the …

[HTML][HTML] Venom and purified toxins of the spectacled cobra (Naja naja) from Pakistan: insights into toxicity and antivenom neutralization

KY Wong, CH Tan, NH Tan - The American journal of tropical …, 2016 - ncbi.nlm.nih.gov
Geographical variations of snake venoms can result in suboptimal effectiveness of Indian
antivenoms that are currently used in most South Asian countries. This study investigated …

Purification and partial characterization of stonustoxin (lethal factor) from Synanceja horrida venom.

CH Poh, R Yuen, HE Khoo, M Chung… - … and physiology. B …, 1991 - europepmc.org
1. The lethal factor of the stonefish (Synanceja horrida) venom, designated as the
stonustoxin, was purified to homogeneity by a two-step procedure on Sephacryl S-200 High …

Phytochemical characterization and phospholipase A2 inhibitory effect of Vitex negundo L. root extracts

S Kusar, Z Saddiqe, MHHB Asad, F Ali… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Snake bites are a critical health issue in many parts of the
world particularly in Asian countries lacking efficient health facilities in rural areas. Cobra is …

Exploring the inhibitory potential of phytochemicals from Vernonia glaberrima leaves against snake venom toxins through computational simulation and experimental …

AJ Yusuf, AI Bugaje, M Sadiq, M Salihu, HW Adamu… - Toxicon, 2024 - Elsevier
Abstract Phospholipase A 2 (PLA 2) is an enzyme present in appreciable quantity in snake
venoms which catalyze the hydrolysis of glycerophospholipids at sn-2 position and promote …

Unveiling the elusive and exotic: Venomics of the Malayan blue coral snake (Calliophis bivirgata flaviceps)

CH Tan, SY Fung, MKK Yap, PK Leong, JL Liew… - Journal of …, 2016 - Elsevier
The venom proteome of the Malayan blue coral snake, Calliophis bivirgata flaviceps from
west Malaysia was investigated by 1D-SDS-PAGE and shotgun-LCMS/MS. A total of 23 …

Intraspecific venom variation of Mexican West Coast Rattlesnakes (Crotalus basiliscus) and its implications for antivenom production

A Colis-Torres, E Neri-Castro, JL Strickland… - Biochimie, 2022 - Elsevier
Intraspecific variation in snake venoms has been widely documented worldwide. However,
there are few studies on this subject in Mexico. Venom characterization studies provide …

Biological activities of Synanceja horrida (stonefish) venom

HE Khoo, R Yuen, CH Poh, CH Tan - Natural Toxins, 1992 - Wiley Online Library
Some biological and neurochemical properties of the venom of stonefish (Syanceja horrida)
were investigated. The venom exhibited oedema‐inducing, haemolytic, hyaluronidase …

Distinctive Distribution of Secretory Phospholipases A2 in the Venoms of Afro-Asian Cobras (Subgenus: Naja, Afronaja, Boulengerina and Uraeus)

CH Tan, KY Wong, NH Tan, TS Ng, KY Tan - Toxins, 2019 - mdpi.com
The protein abundances of phospholipases A2 in cobra venom proteomes appear to vary
among cobra species. To determine the unique distribution of snake venom phospholipases …