Women undergo important changes in sex hormones throughout their lifetime that can
impact cardiovascular disease risk. Whereas the traditional cardiovascular risk factors …

Key Clinical Points Primary Ovarian Insufficiency Primary ovarian insufficiency should be
considered in women younger than 40 years of age who present with new-onset irregular …

Primary ovarian insufficiency (POI) is a rare but important cause of ovarian hormone
deficiency and infertility in women. In addition to causing infertility, POI is associated with …

Abstract The following Consensus Statement is endorsed by The International Menopause
Society, The North American Menopause Society, The Endocrine Society, The European …

The human menopause transition and aging are each associated with an increase in a
variety of health risk factors including, but not limited to, cardiovascular disease …

Objective Neurokinin (NK)-3 and NK-1 receptors have been implicated in the etiology of
vasomotor symptoms (VMS) and sleep disturbances associated with menopause. This …

Background Adequate knowledge and positive attitude toward menopause are important for
women to tackle changes related to menopause. Even though all women experience …

BACKGROUND The effect of postmenopausal hormone therapy (HT) on cardiovascular
disease (CVD) risk remains controversial. OBJECTIVE AND RATIONALE We aimed to …

Abstract Vasomotor symptoms (VMS), genito-urinary syndrome of menopause (GSM), sleep
disturbance, sexual dysfunction and mood disturbance are common during the menopause …

Menopause in human females and subsequent ovarian hormone deficiency, particularly
concerning 17β-estradiol (E2), increase the risk for metabolic dysfunctions associated with …