Metastatic heterogeneity of breast cancer: Molecular mechanism and potential therapeutic targets
Breast cancer is one of the most common malignancies among women throughout the world
and is the major cause of most cancer-related deaths. Several explanations account for the …
and is the major cause of most cancer-related deaths. Several explanations account for the …
Harnessing the immune system against cancer: current immunotherapy approaches and therapeutic targets
Cancer immunotherapy is a rapidly evolving concept that has been given the tag" fifth pillar"
of cancer therapy while radiation therapy, chemotherapy, surgery and targeted therapy …
of cancer therapy while radiation therapy, chemotherapy, surgery and targeted therapy …
[HTML][HTML] Targeting the insulin-like growth factor pathway in hepatocellular carcinoma
M Enguita-Germán, P Fortes - World journal of hepatology, 2014 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths
worldwide. Only 30%-40% of the patients with HCC are eligible for curative treatments …
worldwide. Only 30%-40% of the patients with HCC are eligible for curative treatments …
EMT in cervical cancer: its role in tumour progression and response to therapy
The prognosis of cervical patients significantly decreases as the cancer metastasizes to
other parts of the body. The epithelial to mesenchymal transition (EMT) plays an important …
other parts of the body. The epithelial to mesenchymal transition (EMT) plays an important …
[HTML][HTML] A non-proliferative role of pyrimidine metabolism in cancer
A Siddiqui, P Ceppi - Molecular metabolism, 2020 - Elsevier
Background Nucleotide metabolism is a critical pathway that generates purine and
pyrimidine molecules for DNA replication, RNA synthesis, and cellular bioenergetics …
pyrimidine molecules for DNA replication, RNA synthesis, and cellular bioenergetics …
MicroRNA-375 targets AEG-1 in hepatocellular carcinoma and suppresses liver cancer cell growth in vitro and in vivo
MicroRNAs (miRNAs) are believed to have fundamental roles in tumorigenesis and have
great potential for the diagnosis and treatment of cancer. However, the roles of miRNAs in …
great potential for the diagnosis and treatment of cancer. However, the roles of miRNAs in …
The emerging role of miR‐375 in cancer
MicroRNAs (miRNAs) are evolutionarily conserved, small noncoding RNAs that are believed
to play fundamental roles in various biological processes through regulation of gene …
to play fundamental roles in various biological processes through regulation of gene …
The multifaceted role of MTDH/AEG-1 in cancer progression
Cancer is the result of the progressive acquisition of multiple malignant traits through the
accumulation of genetic or epigenetic alterations. Recent studies have established a …
accumulation of genetic or epigenetic alterations. Recent studies have established a …
Astrocyte elevated gene-1 (AEG-1) functions as an oncogene and regulates angiogenesis
L Emdad, SG Lee, ZZ Su, HY Jeon… - Proceedings of the …, 2009 - National Acad Sciences
Astrocyte-elevated gene-1 (AEG-1) expression is increased in multiple cancers and plays a
central role in Ha-ras-mediated oncogenesis through the phosphatidylinositol 3-kinase …
central role in Ha-ras-mediated oncogenesis through the phosphatidylinositol 3-kinase …
[PDF][PDF] Genomic landscape of copy number aberrations enables the identification of oncogenic drivers in hepatocellular carcinoma
Cancer is a genetic disease with frequent somatic DNA alterations. Studying recurrent copy
number aberrations (CNAs) in human cancers would enable the elucidation of disease …
number aberrations (CNAs) in human cancers would enable the elucidation of disease …