Heart diseases due to myocardial ischemia, such as myocardial infarction or ischemic heart
failure, are major causes of death in developed countries, and their number is unfortunately …

Yellon, Derek M., and James M. Downey. Preconditioning the Myocardium: From Cellular
Physiology to Clinical Cardiology. Physiol Rev 83: 1113-1151, 2003; 10.1152/physrev …

Given the basic need for opioids in the perioperative setting, we investigated associations
between opioid prescription levels and postoperative outcomes using population-based …

Opioids are the most potent of all analgesics. Although traditionally used solely for acute self-
limited conditions and palliation of severe cancer-associated pain, a movement to promote …

Ischaemic heart disease (IHD) remains a major cause of morbidity/mortality globally, firmly
established in W esternized or 'developed'countries and rising in prevalence in developing …

Purpose: The aim of this review of the literature was to evaluate the effectiveness of
anesthetics in protecting the heart against myocardial ischemia-reperfusion injury. Source …

Opioid peptides and exogenous opioids such as morphine are known to exert important
cardiovascular effects. However, until recently, it was not appreciated that activation of …

Ischemic heart disease and myocardial infarction continue to be leading causes of
cardiovascular morbidity and mortality. Activation of opioid, adenosine, bradykinin …

Following a period of ischemia (local restriction of blood supply to a tissue), the restoration of
blood supply to the affected area causes significant tissue damage. This is known as …

Ischemic preconditioning is a well-established phenomenon first described in experimental
preparations in which brief episodes of ischemia/reperfusion applied prior to a longer …