Dynamic combinatorial chemistry: a new methodology comes of age

P Frei, R Hevey, B Ernst - Chemistry–A European Journal, 2019 - Wiley Online Library
Dynamic combinatorial chemistry (DCC) has repeatedly proven to be an effective approach
to generate directed ligand libraries for macromolecular targets. In the absence of an …

Imine-and amine-type macrocycles derived from chiral diamines and aromatic dialdehydes

J Lisowski - Molecules, 2022 - mdpi.com
The condensation of aromatic dialdehydes with chiral diamines, such as 1, 2-trans-
diaminocyclohexane, leads to various enantiopure or meso-type macrocyclic Schiff bases …

Impact and importance of electrostatic potential calculations for predicting structural patterns of hydrogen and halogen bonding

MD Perera, J Desper, AS Sinha, CB Aakeröy - CrystEngComm, 2016 - pubs.rsc.org
The way in which differences in electrostatic potential values can govern how ditopic
hydrogen/halogen-bond acceptors form supramolecular interactions in the solid state has …

Chemically Fuelled Self‐Regulating Gel‐to‐Gel Transition

S Panja, B Dietrich, DJ Adams - ChemSystemsChem, 2020 - Wiley Online Library
Artificial self‐regulating materials can be prepared by exploiting fuel‐driven pathways.
Dynamic covalent bonds are formed and broken reversibly under mild reaction conditions …

Template-controlled synthesis of chiral cyclohexylhemicucurbit [8] uril

E Prigorchenko, M Öeren, S Kaabel… - Chemical …, 2015 - pubs.rsc.org
Enantiomerically pure cyclohexylhemicucurbit [8] uril (cycHC [8]), possessing a barrel-
shaped cavity, has been prepared in high yield on a gram scale from either (R, R, N, N′) …

Probing secondary interactions in biomolecular recognition by dynamic combinatorial chemistry

S Ulrich, P Dumy - Chemical Communications, 2014 - pubs.rsc.org
Artificial multivalent recognition systems offer promising perspectives for developing
synthetic compounds capable of interacting effectively and selectively with biomolecules in …

Dithioacetal exchange: a new reversible reaction for dynamic combinatorial chemistry

AG Orrillo, AM Escalante… - Chemistry–A European …, 2016 - Wiley Online Library
Reversibility of dithioacetal bond formation is reported under acidic mild conditions. Its utility
for dynamic combinatorial chemistry was explored by combining it with orthogonal disulfide …

An “Ingredients” Approach to Functional Self‐Synthesizing Materials: A Metal‐Ion‐Selective, Multi‐Responsive, Self‐Assembled Hydrogel

J Li, I Cvrtila, M Colomb‐Delsuc… - … –A European Journal, 2014 - Wiley Online Library
New methodology for making novel materials is highly desirable. Here, an “ingredients”
approach to functional self‐assembled hydrogels was developed. By designing a building …

Template-triggered emergence of a self-replicator from a dynamic combinatorial library

P Nowak, M Colomb-Delsuc, S Otto… - Journal of the American …, 2015 - ACS Publications
Self-assembly of a specific member of a dynamic combinatorial library (DCL) may lead to
self-replication of this molecule. However, if the concentration of the potential replicator in …

Template-directed self-assembly of dynamic covalent capsules with polar interiors

A Galán, EC Escudero-Adán, P Ballester - Chemical Science, 2017 - pubs.rsc.org
Chiral polyimine molecular capsules with polar interiors have been prepared through
template covalent dynamic self-assembly. An aryl-extended tetraaldehyde calix [4] pyrrole …