Alcoholism: a systems approach from molecular physiology to addictive behavior

R Spanagel - Physiological reviews, 2009 - journals.physiology.org
Alcohol consumption is an integral part of daily life in many societies. The benefits
associated with the production, sale, and use of alcoholic beverages come at an enormous …

Opioid peptides and the control of human ingestive behaviour

MR Yeomans, RW Gray - Neuroscience & Biobehavioral Reviews, 2002 - Elsevier
A variety of evidence suggests that endogenous opioid peptides play a role in the short-term
control of eating. More recently, opioid receptor antagonists like naltrexone have been …

The American Psychiatric Association practice guideline for the pharmacological treatment of patients with alcohol use disorder

VI Reus, LJ Fochtmann, O Bukstein… - American Journal of …, 2018 - Am Psychiatric Assoc
The goal of this guideline1 is to improve the quality of care and treatment outcomes for
patients with alcohol use disorder (AUD), as defined by DSM-5 (American Psychiatric …

Naltrexone decreases craving and alcohol self-administration in alcohol-dependent subjects and activates the hypothalamo–pituitary–adrenocortical axis

SS O'Malley, S Krishnan-Sarin, C Farren, R Sinha… - …, 2002 - Springer
Background: This laboratory study investigated the mechanisms by which the opioid
antagonist, naltrexone, reduces the risk of relapse to heavy drinking in individuals with …

Effect of naltrexone and ondansetron on alcohol cue–induced activation of the ventral striatum in alcohol-dependent people

H Myrick, RF Anton, X Li, S Henderson… - Archives of general …, 2008 - jamanetwork.com
Context Medication for the treatment of alcoholism is currently not particularly robust.
Neuroimaging techniques might predict which medications could be useful in the treatment …

The role of the brain reward system in depression

CA Naranjo, LK Tremblay, UE Busto - Progress in Neuro …, 2001 - Elsevier
The goal of this review is to familiarize the reader about the potential involvement of the
brain reward system (BRS) in symptoms of Major Depressive Disorder (MDD). The authors …

Opioids and alcoholism

LM Oswald, GS Wand - Physiology & behavior, 2004 - Elsevier
Although far from conclusive, evidence implicating the endogenous opioid system in the
development and maintenance of alcoholism is growing. Currently available data suggest …

[HTML][HTML] Influence of the endogenous opioid system on high alcohol consumption and genetic predisposition to alcoholism

C Gianoulakis - Journal of Psychiatry and Neuroscience, 2001 - ncbi.nlm.nih.gov
There is increasing evidence supporting a link between the endogenous opioid system and
excessive alcohol consumption. Acute or light alcohol consumption stimulates the release of …

[HTML][HTML] Comorbidity of alcoholism and psychiatric disorders: an overview

IL Petrakis, G Gonzalez, R Rosenheck… - Alcohol Research & …, 2002 - ncbi.nlm.nih.gov
People with alcohol use disorders often have co-occurring psychiatric disorders, but they
frequently do not receive specialized substance abuse treatment that addresses both …

Pharmacotherapy of alcohol dependence: a review of the clinical data

K Mann - CNS drugs, 2004 - Springer
Over the last 20 years, the role of adjuvant pharmacotherapy in optimising outcome in
rehabilitation programmes for alcohol-dependent patients has become increasingly evident …