Recent progress in the identification of selective butyrylcholinesterase inhibitors for Alzheimer's disease

Q Li, H Yang, Y Chen, H Sun - European journal of medicinal chemistry, 2017 - Elsevier
Alzheimer's disease (AD) is one of the most prevalent neurodegenerative disorders with
notable factor of dysfunction in cholinergic system. Low ACh level can be observed in the …

Rhein: a review of pharmacological activities

YX Zhou, W Xia, W Yue, C Peng… - Evidence‐based …, 2015 - Wiley Online Library
Rhein (4, 5‐dihydroxyanthraquinone‐2‐carboxylic acid) is a lipophilic anthraquinone
extensively found in medicinal herbs, such as Rheum palmatum L., Cassia tora L …

[图书][B] Genetic Resources, Chromosome Engineering, and Crop Improvement: Cereals, Volume 2

RJ Singh, PP Jauhar - 2006 - taylorfrancis.com
Summarizing landmark research, Volume 2 of this essential series furnishes information on
the availability of germplasm resources that breeders can exploit for producing high-yielding …

A comprehensive and system review for the pharmacological mechanism of action of rhein, an active anthraquinone ingredient

H Sun, G Luo, D Chen, Z Xiang - Frontiers in pharmacology, 2016 - frontiersin.org
Rhein is a major medicinal ingredient isolated from several traditional Chinese medicines,
including Rheum palmatum L., Aloe barbadensis Miller, Cassia angustifolia Vahl., and …

Application of molecular imprinting polymers in separation of active compounds from plants

L Zhang, H Yu, H Chen, Y Huang, I Bakunina… - Fitoterapia, 2023 - Elsevier
Molecular imprinting technique is becoming an appealing and prominent strategy to
synthesize materials for target recognition and rapid separation. In recent years, it has been …

Vascular endothelial growth factor (VEGF), mast cells and inflammation

YB Shaik-Dasthagirisaheb, G Varvara… - International journal …, 2013 - journals.sagepub.com
Vascular endothelial growth factor (VEGF) is one of the most important inducers of
angiogenesis, therefore blocking angiogenesis has led to great promise in the treatment of …

Rhein improves renal lesion and ameliorates dyslipidemia in db/db mice with diabetic nephropathy

Q Gao, WS Qin, ZH Jia, JM Zheng, CH Zeng… - Planta …, 2010 - thieme-connect.com
Abstract Rhein (4, 5-dihydroxyanthraquinone-2-carboxylic acid) is purified from rhubarb
(Rheum officinale), a widely used traditional Chinese herb. In our previous studies, rhein …

Anti-influenza A virus activity of rhein through regulating oxidative stress, TLR4, Akt, MAPK, and NF-κB signal pathways

QW Wang, Y Su, JT Sheng, LM Gu, Y Zhao, XX Chen… - PLoS …, 2018 - journals.plos.org
Rhein, an anthraquinone compound existing in many traditional herbal medicines, has anti-
inflammatory, antioxidant, antitumor, antiviral, hepatoprotective, and nephroprotective …

Multitarget tacrine hybrids with neuroprotective properties to confront Alzheimer's disease

K Spilovska, J Korabecny… - Current Topics in …, 2017 - ingentaconnect.com
Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder. Several hallmarks
such as β-amyloid (Aβ) aggregation underlying amyloid plaque formation, Τ …

Rhein protects against acetaminophen-induced hepatic and renal toxicity

YL Zhao, GD Zhou, HB Yang, JB Wang… - Food and chemical …, 2011 - Elsevier
This study investigated the possible protective effects and mechanism of rhein on
Acetaminophen (APAP)-induced hepatotoxicity and nephrotoxicity in rats. Treatment of rats …