Over the past two decades, obesity has been one of the major public health concerns in
most countries. In the search for new molecules that could be used for the treatment of …

Brown adipose tissue (BAT), a thermoregulatory organ known to promote energy
expenditure, has been extensively studied as a potential avenue to combat obesity …

OBJECTIVE Diabetes prevalence and incidence increase among individuals with
hypothyroidism but also among those with hyperthyroxinemia, which seems contradictory …

Obesity leads to multiple health problems, including diabetes, fatty liver, and even cancer.
Here, we report that urolithin A (UA), a gut-microflora–derived metabolite of pomegranate …

The growing focus on brown adipocytes has spurred an interest in their potential benefits for
metabolic diseases. Brown and beige (or brite) adipocytes express high levels of uncoupling …

Bone marrow-derived mesenchymal stem cells (BM-MSCs) are multipotent stromal cells that
have a critical role in the maintenance of skeletal tissues such as bone, cartilage, and the fat …

Abstract General Control Non-repressed 5 protein (GCN5), encoded by the mammalian
gene Kat2a, is the first histone acetyltransferase discovered to link histone acetylation to …

Understanding the mammalian energy balance can pave the way for future therapeutics that
enhance energy expenditure as an anti-obesity and anti-diabetic strategy. Several studies …

Persistent uptake of high‐calorie diets induces the storage of excessive lipid in visceral
adipose tissue. Lipids secreted from obese adipose tissue are accumulated in peripheral …

Diverse groups of factors are leading to increased weight gain and obesity, such as certain
genetic phenotypes, neuroendocrine disturbances, the administration of some drugs …